Title : Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor.

Pub. Date : 2017 Jan 4

PMID : 27871908






2 Functional Relationships(s)
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1 The Pregnane X (PXR), Vitamin D (VDR) and Farnesoid X (FXR) nuclear receptors have been shown to be receptors of bile acids controlling their detoxification or synthesis. Bile Acids and Salts nuclear receptor subfamily 1 group I member 2 Homo sapiens
2 Whether the acetylated bile acid derivatives are novel endogenous ligands of PXR with detoxification or physiological functions should be further studied in ongoing experiments. Bile Acids and Salts nuclear receptor subfamily 1 group I member 2 Homo sapiens