Pub. Date : 2018 Jun
PMID : 30464886
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Recent Findings: The genetic variations associated with AT-DILI have been identified in the genomic regions within or near genes encoding proteins in the following pathways: drug metabolizing enzymes (NAT2, CYP2E1, and GSTs), accumulation of bile acids, lipids, and heme metabolites (CYP7A1, BSEP, UGTs, and PXR), immune adaptation (HLAs and TNF-alpha), and oxidant challenge (TXNRD1, SOD1, BACH1, and MAFK). | Bile Acids and Salts | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |