Adenosine Diphosphate

purinergic receptor P2Y12 ; Homo sapiens







236 Article(s)
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1 35191835 TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia. 2022 Feb 22 1
2 35514261 Evidence for a PI3-kinase independent pathway in the regulation of Rap1b activation downstream of the P2Y12 receptor in platelets. 2022 May 6 2
3 31949019 Low-dose Btk inhibitors selectively block platelet activation by CLEC-2. 2021 Jan 1 1
4 33309519 Molecular pharmacology of P2Y receptor subtypes. 2021 May 1
5 33652345 Serum Albumin, Body Mass Index, and Preceding Xa and P2Y12 Inhibitors Predict Prognosis of Recurrent Ischemic Stroke. 2021 May 2
6 33819246 Stronger inhibitory effects of Ticagrelor plus aspirin compared with Clopidogrel plus aspirin on arachidonic acid-induced platelet aggregation in patients with acute coronary syndrome with PCI. 2021 Feb 1
7 34143384 Clinical validation of AggreGuide A-100 ADP, a novel assay for assessing the antiplatelet effect of oral P2Y12 antagonists. 2021 Jul 1
8 34748820 NOD2-mediated P2Y12 upregulation increases platelet activation and thrombosis in sepsis. 2021 Dec 1
9 34752329 Purinergic GPCR transmembrane residues involved in ligand recognition and dimerization. 2021 1
10 30744477 The effect of smoking on residual platelet reactivity to clopidogrel: a systematic review and meta-analysis. 2020 1
11 30810440 Assessment of neonatal, cord, and adult platelet granule trafficking and secretion. 2020 1
12 31649128 Severe bleeding and absent ADP-induced platelet aggregation associated with inherited combined CalDAG-GEFI and P2Y12 deficiencies. 2020 Jul 1
13 31808055 ADP exerts P2Y12 -dependent and P2Y12 -independent effects on primary human T cell responses to stimulation. 2020 Mar 5
14 31968611 Antiplatelet Drug Ticagrelor Enhances Chemotherapeutic Efficacy by Targeting the Novel P2Y12-AKT Pathway in Pancreatic Cancer Cells. 2020 Jan 20 1
15 32034708 Cross-Talk in Nucleotide Signaling in Glioma C6 Cells. 2020 2
16 32365642 Regulation of Microglial Functions by Purinergic Mechanisms in the Healthy and Diseased CNS. 2020 Apr 29 1
17 32368161 Impact of Routine Platelet Reactivity Testing with VerifyNow Assay on Antiplatelet Choice After Percutaneous Coronary Intervention. 2020 1
18 32464678 Platelet Purinergic Receptors in Thrombosis and Inflammation. 2020 May 1
19 32803122 The Impact of Cold Storage on Adenosine Diphosphate-Mediated Platelet Responsiveness. 2020 Jul 1
20 32867554 Purinergic Dysfunction in Pulmonary Arterial Hypertension. 2020 Sep 15 1
21 29671861 P2Y12 antagonist ticagrelor inhibits the release of procoagulant extracellular vesicles from activated platelets. 2019 2
22 30302530 The role of P2Y12 receptor in ischemic stroke of atherosclerotic origin. 2019 Jan 1
23 30475578 The Inhibition by Guanfu Base A of Neuropathic Pain Mediated by P2Y12 Receptor in Dorsal Root Ganglia. 2019 Mar 20 1
24 30673942 "Blueprinting" thrombogenicity and antithrombotic drug response at the bedside in patients presenting emergently with symptoms of acute stroke. 2019 Feb 1
25 30734681 Structure Activity Relationship of 4-Amino-2-thiopyrimidine Derivatives as Platelet Aggregation Inhibitors. 2019 1
26 31376607 Impaired adenylate cyclase signaling in acute myocardial ischemia: Impact on effectiveness of P2Y12 receptor antagonists. 2019 Sep 2
27 31591378 ADP secreted by dying melanoma cells mediates chemotaxis and chemokine secretion of macrophages via the purinergic receptor P2Y12. 2019 Oct 7 2
28 31624788 Platelet CD40 ligand and bleeding during P2Y12 inhibitor treatment in acute coronary syndrome. 2019 Oct 2
29 28511553 Whole Blood Platelet Aggregation Test and Prediction of Hemostatic Difficulty After Tooth Extraction in Patients Receiving Antiplatelet Therapy. 2018 Jan 2
30 28523947 Potentiation of TRAP-6-induced platelet dense granule release by blockade of P2Y12 signaling with MRS2395. 2018 Jun 2
31 28921624 Pharmacodynamics and pharmacokinetics of ticagrelor vs. clopidogrel in patients with acute coronary syndromes and chronic kidney disease. 2018 Jan 2
32 29171876 Decreased platelet inhibition by P2Y12 receptor blockers in anaemia. 2018 Jan 2
33 29188558 Breakthrough in GPCR Crystallography and Its Impact on Computer-Aided Drug Design. 2018 1
34 29322294 Ticagrelor inhibits platelet-tumor cell interactions and metastasis in human and murine breast cancer. 2018 Feb 1
35 29350995 A Review of Analytical Methods for the determination of Clopidogrel in Pharmaceuticals and Biological Matrices. 2018 Mar 4 2
36 29439388 Inhibitory Effect of Flavonolignans on the P2Y12 Pathway in Blood Platelets. 2018 Feb 10 1
37 29456511 P2Y12 Receptors in Tumorigenesis and Metastasis. 2018 1
38 29468430 Impaired aspirin-mediated platelet function inhibition in resuscitated patients with acute myocardial infarction treated with therapeutic hypothermia: a prospective, observational, non-randomized single-centre study. 2018 Feb 21 1
39 29574692 P2Y12 receptor modulation of ADP-evoked intracellular Ca2+ signalling in THP-1 human monocytic cells. 2018 Jun 6
40 29575062 Restored response to ADP downstream of purinergic P2Y12 receptor in apheresis platelets after pathogen-reducing xenon flash treatment. 2018 May 1
41 29902630 The role of agonist-induced activation and inhibition for the regulation of purinergic receptor expression in human platelets. 2018 Aug 2
42 29968812 Lipid rafts are essential for release of phosphatidylserine-exposing extracellular vesicles from platelets. 2018 Jul 3 1
43 30012347 Response to aspirin therapy in patients with myeloproliferative neoplasms depends on the platelet count. 2018 Oct 1
44 30199785 Study on antiplatelet effect of a new thiophenopyridine platelets P2Y12 receptor antagonist DV-127. 2018 Oct 1
45 30222974 Reorganization of platelet membrane sphingomyelins by adenosine diphosphate and ticagrelor. 2018 Nov 2
46 30346865 Effects of platelet dysfunction and platelet transfusion on outcomes in traumatic brain injury patients. 2018 1
47 30445678 Cangrelor Induces More Potent Platelet Inhibition without Increasing Bleeding in Resuscitated Patients. 2018 Nov 15 4
48 27628007 Role of P2Y12 Receptor in Thrombosis. 2017 1
49 27848264 Underlying mechanism and specific prevention of hemolysis-induced platelet activation. 2017 Sep 2
50 27885904 The effect of P2Y12 inhibition on platelet activation assessed with aggregation- and flow cytometry-based assays. 2017 Sep 1