Title : Decreased platelet inhibition by P2Y12 receptor blockers in anaemia.

Pub. Date : 2018 Jan

PMID : 29171876






2 Functional Relationships(s)
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1 BACKGROUND: Anaemic patients undergoing angioplasty and stenting are at an increased risk of ischaemic events, which may be caused by an inadequate response to antiplatelet therapy with adenosine diphosphate (ADP) P2Y12 inhibitors. Adenosine Diphosphate purinergic receptor P2Y12 Homo sapiens
2 Moreover, by LTA maximal aggregation in response to ADP was significantly higher in patients with anaemia in both groups (both P < .05), and anaemic patients in group 1 had a significantly higher on-treatment platelet reactivity by the VerifyNow P2Y12 assay and the Impact-R than those without anaemia (both P < .001). Adenosine Diphosphate purinergic receptor P2Y12 Homo sapiens