| 201 |
16194206 | A differential role of the platelet ADP receptors P2Y1 and P2Y12 in Rac activation. | 2005 Oct |
1 |
| 202 |
16194207 | Impaired platelet function in a patient with P2Y12 deficiency caused by a mutation in the translation initiation codon. | 2005 Oct |
1 |
| 203 |
16228296 | PI3-kinase is essential for ADP-stimulated integrin alpha(IIb)beta3-mediated platelet calcium oscillation, implications for P2Y receptor pathways in integrin alpha(IIb)beta3-initiated signaling cross-talks. | 2005 Dec |
1 |
| 204 |
16236603 | Evidence that the purinergic receptor P2Y12 potentiates platelet shape change by a Rho kinase-dependent mechanism. | 2005 Nov |
3 |
| 205 |
16268477 | Stereoselective inhibition of human platelet aggregation by R-138727, the active metabolite of CS-747 (prasugrel, LY640315), a novel P2Y12 receptor inhibitor. | 2005 Sep |
2 |
| 206 |
14645014 | The plaque lipid lysophosphatidic acid stimulates platelet activation and platelet-monocyte aggregate formation in whole blood: involvement of P2Y1 and P2Y12 receptors. | 2004 Apr 1 |
1 |
| 207 |
14670370 | Inhibition of ADP-induced intracellular Ca2+ responses and platelet aggregation by the P2Y12 receptor antagonists AR-C69931MX and clopidogrel is enhanced by prostaglandin E1. | 2004 Jan |
1 |
| 208 |
14706855 | Costimulation of the Gi-coupled ADP receptor and the Gq-coupled TXA2 receptor is required for ERK2 activation in collagen-induced platelet aggregation. | 2004 Jan 2 |
1 |
| 209 |
15140134 | Different G protein-coupled signaling pathways are involved in alpha granule release from human platelets. | 2004 Jun |
1 |
| 210 |
15203713 | Collagen-induced generation of platelet-derived microparticles in whole blood is dependent on ADP released from red blood cells and calcium ions. | 2004 Jun |
1 |
| 211 |
15213852 | ADP secretion and subsequent P2Y12 receptor signalling play a crucial role in thrombin-induced ERK2 activation in human platelets. | 2004 Jul |
2 |
| 212 |
15265806 | Synergistic action between inhibition of P2Y12/P2Y1 and P2Y12/thrombin in ADP- and thrombin-induced human platelet activation. | 2004 Aug |
2 |
| 213 |
15308557 | ADP receptor P2Y12 is expressed in vascular smooth muscle cells and stimulates contraction in human blood vessels. | 2004 Oct |
3 |
| 214 |
15333577 | Platelet adhesion and signaling induced by the octapeptide primary binding sequence (KOGEOGPK) from type III collagen. | 2004 Sep |
1 |
| 215 |
15345752 | Induction of novel agonist selectivity for the ADP-activated P2Y1 receptor versus the ADP-activated P2Y12 and P2Y13 receptors by conformational constraint of an ADP analog. | 2004 Dec |
1 |
| 216 |
12578987 | Molecular bases of defective signal transduction in the platelet P2Y12 receptor of a patient with congenital bleeding. | 2003 Feb 18 |
2 |
| 217 |
12615691 | In vivo blockade of platelet ADP receptor P2Y12 reduces embolus and thrombus formation but not thrombus stability. | 2003 Mar 1 |
2 |
| 218 |
12912815 | Adenosine diphosphate-induced platelet aggregation is associated with P2Y12 gene sequence variations in healthy subjects. | 2003 Aug 26 |
2 |
| 219 |
12913786 | Scientific and therapeutic insights into the role of the platelet P2Y12 receptor in thrombosis. | 2003 Sep |
3 |
| 220 |
14610915 | ADP receptor antagonists as antiplatelet therapeutics. | 2003 May |
1 |
| 221 |
14662702 | P2Y12 H2 haplotype is associated with peripheral arterial disease: a case-control study. | 2003 Dec 16 |
1 |
| 222 |
11756171 | Adenosine diphosphate (ADP)-induced thromboxane A(2) generation in human platelets requires coordinated signaling through integrin alpha(IIb)beta(3) and ADP receptors. | 2002 Jan 1 |
2 |
| 223 |
11815620 | A Gi-dependent pathway is required for activation of the small GTPase Rap1B in human platelets. | 2002 Apr 5 |
1 |
| 224 |
11950711 | Role of ADP receptor P2Y(12) in platelet adhesion and thrombus formation in flowing blood. | 2002 Apr 1 |
1 |
| 225 |
12353080 | Inhibition of ADP-induced P-selectin expression and platelet-leukocyte conjugate formation by clopidogrel and the P2Y12 receptor antagonist AR-C69931MX but not aspirin. | 2002 Sep |
1 |
| 226 |
12806027 | P2 receptors and platelet activation. | 2002 Feb 13 |
2 |
| 227 |
11104774 | ADP is the cognate ligand for the orphan G protein-coupled receptor SP1999. | 2001 Mar 16 |
3 |
| 228 |
11413167 | Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs. | 2001 Jun |
1 |
| 229 |
11502873 | Molecular cloning of the platelet P2T(AC) ADP receptor: pharmacological comparison with another ADP receptor, the P2Y(1) receptor. | 2001 Sep |
3 |
| 230 |
10751543 | On the mechanism of plasmin-induced platelet aggregation. Implications of the dual role of granule ADP. | 2000 Jun 1 |
1 |
| 231 |
10960076 | ADP is not an agonist at P2X(1) receptors: evidence for separate receptors stimulated by ATP and ADP on human platelets. | 2000 Sep |
2 |
| 232 |
10446085 | Specific impairment of human platelet P2Y(AC) ADP receptor-mediated signaling by the antiplatelet drug clopidogrel. | 1999 Aug |
1 |
| 233 |
10506165 | Molecular mechanism of thromboxane A(2)-induced platelet aggregation. Essential role for p2t(ac) and alpha(2a) receptors. | 1999 Oct 8 |
1 |
| 234 |
10544922 | Role of intracellular signaling events in ADP-induced platelet aggregation. | 1999 Oct |
2 |
| 235 |
9653141 | Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation. | 1998 Jul 7 |
1 |
| 236 |
16793695 | Hereditary defect of the platelet ADP receptor(s). | 1998 |
3 |