Title : Structure Activity Relationship of 4-Amino-2-thiopyrimidine Derivatives as Platelet Aggregation Inhibitors.

Pub. Date : 2019

PMID : 30734681






1 Functional Relationships(s)
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1 Recently, the important role in the platelet aggregation of adenosine diphosphate (ADP)-activated P2Y12 and P2Y1 receptors, Gprotein coupled receptors of the P2 purinergic family, has emerged, and their inhibitors are explored as potential therapeutic antithrombotics. Adenosine Diphosphate purinergic receptor P2Y12 Homo sapiens