repaglinide

solute carrier organic anion transporter family member 1B1 ; Homo sapiens







25 Article(s)
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1 33088647 Severe hypoglycemia caused by a small dose of repaglinide and concurrent use of nilotinib and febuxostat in a patient with type 2 diabetes. 2020 Oct 1
2 30636597 Effects of CYP2C8 and SLCO1B1 Genetic Polymorphisms on Repaglinide Pharmacokinetics: A Systematic Review and Meta-Analysis. 2019 2
3 31129789 Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug-Drug-Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole. 2019 Dec 2
4 28653144 Explaining Ethnic Variability of Transporter Substrate Pharmacokinetics in Healthy Asian and Caucasian Subjects with Allele Frequencies of OATP1B1 and BCRP: A Mechanistic Modeling Analysis. 2018 Apr 1
5 29748863 Repaglinide-irbesartan drug interaction: effects of SLCO1B1 polymorphism on repaglinide pharmacokinetics and pharmacodynamics in Chinese population. 2018 Aug 5
6 30260092 A Strategy to Refine the Phenotyping Approach and Its Implementation to Predict Drug Clearance: A Physiologically Based Pharmacokinetic Simulation Study. 2018 Dec 1
7 28479356 Quantitative Analysis of Complex Drug-Drug Interactions Between Repaglinide and Cyclosporin A/Gemfibrozil Using Physiologically Based Pharmacokinetic Models With In Vitro Transporter/Enzyme Inhibition Data. 2017 Sep 2
8 27457785 Clarification of the Mechanism of Clopidogrel-Mediated Drug-Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro Information. 2016 Oct 2
9 27543206 Transporter Expression in Liver Tissue from Subjects with Alcoholic or Hepatitis C Cirrhosis Quantified by Targeted Quantitative Proteomics. 2016 Nov 1
10 24623479 Reduced physiologically-based pharmacokinetic model of repaglinide: impact of OATP1B1 and CYP2C8 genotype and source of in vitro data on the prediction of drug-drug interaction risk. 2014 Sep 4
11 24971633 Glucuronidation converts clopidogrel to a strong time-dependent inhibitor of CYP2C8: a phase II metabolite as a perpetrator of drug-drug interactions. 2014 Oct 1
12 23393219 Quantitative prediction of repaglinide-rifampicin complex drug interactions using dynamic and static mechanistic models: delineating differential CYP3A4 induction and OATP1B1 inhibition potential of rifampicin. 2013 May 1
13 23625433 Effect of pitavastatin in different SLCO1B1 backgrounds on repaglinide pharmacokinetics and pharmacodynamics in healthy Chinese males. 2013 May 3
14 23153186 CYP2C metabolism of oral antidiabetic drugs--impact on pharmacokinetics, drug interactions and pharmacogenetic aspects. 2012 Dec 1
15 21327909 Effects of SLCO1B1 polymorphisms on the pharmacokinetics and pharmacodynamics of repaglinide in healthy Chinese volunteers. 2011 Jul 5
16 22041697 [Genetic polymorphisms of SLCO1B1 for drug pharmacokinetics and its clinical implications]. 2011 3
17 20406215 SLCO1B1 polymorphism and oral antidiabetic drugs. 2010 Oct 5
18 19785645 Impact of OATP transporters on pharmacokinetics. 2009 Oct 1
19 17923851 Characterization of novel CYP2C8 haplotypes and their contribution to paclitaxel and repaglinide metabolism. 2008 Aug 1
20 18187595 Different effects of SLCO1B1 polymorphism on the pharmacokinetics and pharmacodynamics of repaglinide and nateglinide. 2008 Mar 2
21 18823304 The effect of SLCO1B1 polymorphism on repaglinide pharmacokinetics persists over a wide dose range. 2008 Dec 3
22 18854776 Effects of the SLCO1B1*1B haplotype on the pharmacokinetics and pharmacodynamics of repaglinide and nateglinide. 2008 Nov 7
23 19238654 Effects of gemfibrozil and atorvastatin on the pharmacokinetics of repaglinide in relation to SLCO1B1 polymorphism. 2008 Oct 5
24 16796707 Effect of SLCO1B1 genetic polymorphism on the pharmacokinetics of nateglinide. 2006 Nov 4
25 16198658 Cyclosporine markedly raises the plasma concentrations of repaglinide. 2005 Oct 3