Pub. Date : 2018 Aug
PMID : 29748863
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Repaglinide-irbesartan drug interaction: effects of SLCO1B1 polymorphism on repaglinide pharmacokinetics and pharmacodynamics in Chinese population. | repaglinide | solute carrier organic anion transporter family member 1B1 | Homo sapiens |
| 2 | Clinical data from single dose of repaglinide indicated SLCO1B1 c.521 T>C polymorphism influenced the PK and PD of repaglinide in healthy Chinese-Han male volunteers. | repaglinide | solute carrier organic anion transporter family member 1B1 | Homo sapiens |
| 3 | Clinical data from single dose of repaglinide indicated SLCO1B1 c.521 T>C polymorphism influenced the PK and PD of repaglinide in healthy Chinese-Han male volunteers. | repaglinide | solute carrier organic anion transporter family member 1B1 | Homo sapiens |
| 4 | CONCLUSION: SLCO1B1 c.521 T>C polymorphism affects the PK of repaglinide in Chinese population. | repaglinide | solute carrier organic anion transporter family member 1B1 | Homo sapiens |
| 5 | Irbesartan increased repaglinide exposure in subjects with SLCO1B1 c.521 TT genotype, but not SLCO1B1 c.521 TC genotype. | repaglinide | solute carrier organic anion transporter family member 1B1 | Homo sapiens |