1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine

cytochrome c oxidase II, mitochondrial ; Mus musculus







16 Article(s)
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1 34587406 Protective Effect of Isopulegol in Alleviating Neuroinflammation in Lipopolysaccharide-Induced BV-2 Cells and in Parkinson Disease Model Induced with MPTP. 2021 1
2 31251998 Phloretin attenuates behavior deficits and neuroinflammatory response in MPTP induced Parkinson's disease in mice. 2019 Sep 1 1
3 26108182 Inhibition of Calpain Activation Protects MPTP-Induced Nigral and Spinal Cord Neurodegeneration, Reduces Inflammation, and Improves Gait Dynamics in Mice. 2015 Oct 1
4 23703110 Fish oil, melatonin and vitamin E attenuates midbrain cyclooxygenase-2 activity and oxidative stress after the administration of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine. 2013 Dec 1
5 21291942 Targeting oxidative stress, mitochondrial dysfunction and neuroinflammatory signaling by selective cyclooxygenase (COX)-2 inhibitors mitigates MPTP-induced neurotoxicity in mice. 2011 Jun 1 3
6 21376018 Possible role of propofol's cyclooxygenase-inhibiting property in alleviating dopaminergic neuronal loss in the substantia nigra in an MPTP-induced murine model of Parkinson's disease. 2011 Apr 28 1
7 21970803 Preventive and therapeutic effects of caffeic acid against inflammatory injury in striatum of MPTP-treated mice. 2011 Nov 30 1
8 19604516 JNK inhibitor protects dopaminergic neurons by reducing COX-2 expression in the MPTP mouse model of subacute Parkinson's disease. 2009 Oct 15 5
9 19861252 [P38MAPK pathway regulates COX-2 and caspase-3 expression in a mouse model of Parkinson disease]. 2009 Oct 1
10 17715026 [Effect of phosphorylated c-Jun expression on COX-2 expression in the substantia nigra of MPTP mouse model of subacute Parkinson disease]. 2007 Aug 4
11 16566823 Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease. 2006 Mar 27 3
12 14704277 JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease. 2004 Jan 13 2
13 15306248 Cyclooxygenases mRNA and protein expression in striata in the experimental mouse model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration to mouse. 2004 Sep 3 3
14 14561922 COX-2-deficient mice are less prone to MPTP-neurotoxicity than wild-type mice. 2003 Oct 27 1
15 12183047 Cyclooxygenase-2-deficient mice are resistant to 1-methyl-4-phenyl1, 2, 3, 6-tetrahydropyridine-induced damage of dopaminergic neurons in the substantia nigra. 2002 Sep 6 6
16 11180504 Inhibition of the cyclooxygenase isoenzymes COX-1 and COX-2 provide neuroprotection in the MPTP-mouse model of Parkinson's disease. 2001 Feb 5