Title : JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease.

Pub. Date : 2004 Jan 13

PMID : 14704277






2 Functional Relationships(s)
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1 Furthermore, we have identified cyclooxygenase (COX) 2 as a molecular target of JNK activation and demonstrated that COX-2 is indispensable for MPTP-induced dopaminergic cell death. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine cytochrome c oxidase II, mitochondrial Mus musculus
2 Furthermore, we have identified cyclooxygenase (COX) 2 as a molecular target of JNK activation and demonstrated that COX-2 is indispensable for MPTP-induced dopaminergic cell death. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine cytochrome c oxidase II, mitochondrial Mus musculus