Title : Activation of c-Raf-1 by Ras and Src through different mechanisms: activation in vivo and in vitro.

Pub. Date : 1997 May 1

PMID : 9171352






1 Functional Relationships(s)
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1 Ras was the only component in these membranes required for activation, as purified recombinant farnesylated K-Ras.GTP, but not non-farnesylated K-Ras.GTP or farnesylated K-Ras.GDP, was able to activate c-Raf-1 to the same degree as intact H-RasG12V membranes. Guanosine Triphosphate KRAS proto-oncogene, GTPase Homo sapiens