Title : Ras activates the epithelial Na(+) channel through phosphoinositide 3-OH kinase signaling.

Pub. Date : 2004 Sep 3

PMID : 15215250






2 Functional Relationships(s)
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1 Aldosterone induces expression and activation of the GTP-dependent signaling switch K-Ras. Guanosine Triphosphate KRAS proto-oncogene, GTPase Homo sapiens
2 We demonstrate here that K-Ras activates human ENaC reconstituted in Chinese hamster ovary cells in a GTP-dependent manner. Guanosine Triphosphate KRAS proto-oncogene, GTPase Homo sapiens