Title : KRAS-specific Amino Acid Substitutions are Associated With Different Responses to Chemotherapy in Advanced Non-small-cell Lung Cancer.

Pub. Date : 2018 Nov

PMID : 30217639






2 Functional Relationships(s)
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1 PATIENTS AND METHODS: We retrospectively reviewed data from 1190 patients with KRAS mutations who underwent first-line platinum-based chemotherapy for stage IV NSCLC. Platinum KRAS proto-oncogene, GTPase Homo sapiens
2 CONCLUSION: KRAS-specific AAS appears to induce different responses to chemotherapy regimens after first-line platinum-based chemotherapy in advanced NSCLC. Platinum KRAS proto-oncogene, GTPase Homo sapiens