Pub. Date : 2022 Apr 20
PMID : 35565194
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | When treated with first-line platinum doublet (n = 195), KRASMUT was a negative factor for survival (p = 0.018), with median OS of 9 months vs. KRASWT at 11 months. | Platinum | KRAS proto-oncogene, GTPase | Homo sapiens |
2 | kRAS mutations are associated with better response to treatment with immune checkpoint blockade and worse response to platinum doublet chemotherapy as well as shorter general OS in Stage IV NSCLC. | Platinum | KRAS proto-oncogene, GTPase | Homo sapiens |