Pub. Date : 2014 Jan
PMID : 24139827
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Clinical outcome with platinum-based chemotherapy in patients with advanced nonsquamous EGFR wild-type non-small-cell lung cancer segregated according to KRAS mutation status. | Platinum | KRAS proto-oncogene, GTPase | Homo sapiens |
| 2 | BACKGROUND: We hypothesized that KRAS mutations function as a marker of poor sensitivity to first-line platinum-based chemotherapy in patients with advanced nonsquamous EGFR wild-type (WT) non-small-cell lung cancer (NSCLC). | Platinum | KRAS proto-oncogene, GTPase | Homo sapiens |
| 3 | CONCLUSION: KRAS mutation appears to negatively affect sensitivity to first-line platinum-based chemotherapy in patients with advanced nonsquamous EGFR WT NSCLC. | Platinum | KRAS proto-oncogene, GTPase | Homo sapiens |