Title : Characterization of distinct types of KRAS mutation and its impact on first-line platinum-based chemotherapy in Chinese patients with advanced non-small cell lung cancer.

Pub. Date : 2017 Dec

PMID : 29163686






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Characterization of distinct types of KRAS mutation and its impact on first-line platinum-based chemotherapy in Chinese patients with advanced non-small cell lung cancer. Platinum KRAS proto-oncogene, GTPase Homo sapiens
2 We performed this retrospective study to investigate whether the KRAS mutation status and its subtypes could predict the effect of first-line platinum-based chemotherapy in Chinese patients with non-small cell lung cancer (NSCLC). Platinum KRAS proto-oncogene, GTPase Homo sapiens
3 In conclusion, KRAS mutation was a negative predictive factor of PFS in Chinese patients with advanced NSCLC who received first platinum-based chemotherapy. Platinum KRAS proto-oncogene, GTPase Homo sapiens