Title : KRAS mutations affect prognosis of non-small-cell lung cancer patients treated with first-line platinum containing chemotherapy.

Pub. Date : 2015 Oct 20

PMID : 26416458






3 Functional Relationships(s)
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1 KRAS mutations affect prognosis of non-small-cell lung cancer patients treated with first-line platinum containing chemotherapy. Platinum KRAS proto-oncogene, GTPase Homo sapiens
2 The aim of this planned ancillary study within the TAILOR trial was to assess the prognostic value of KRAS mutations in advanced NSCLC patients treated with platinum-based first-line chemotherapy. Platinum KRAS proto-oncogene, GTPase Homo sapiens
3 This study, with all consecutive patients genotyped, indicates that the presence of KRAS mutations has a mild negative impact on OS in advanced NSCLC patient treated with a first-line platinum-containing regimen. Platinum KRAS proto-oncogene, GTPase Homo sapiens