| 1 |
35191674 | Aspartic Acid-Assisted Size-Controllable Synthesis of Nanoscale Spherical Covalent Organic Frameworks with Chiral Interfaces for Inhibiting Amyloid-β Fibrillation. | 2022 Mar 21 |
1 |
| 2 |
35347731 | Mass spectrometric studies of the variety of beta-amyloid proteoforms in Alzheimer's disease. | 2022 Mar 28 |
1 |
| 3 |
35426495 | Enhanced ion mobility resolution of Abeta isomers from human brain using high-resolution demultiplexing software. | 2022 Apr 15 |
2 |
| 4 |
32830360 | Membrane dynamics of γ-secretase with the anterior pharynx-defective 1B subunit. | 2021 Jan |
1 |
| 5 |
33928245 | Quantification of N-terminal amyloid-β isoforms reveals isomers are the most abundant form of the amyloid-β peptide in sporadic Alzheimer's disease. | 2021 |
1 |
| 6 |
31922154 | Complete identification of all 20 relevant epimeric peptides in β-amyloid: a new HPLC-MS based analytical strategy for Alzheimer's research. | 2020 Feb 4 |
2 |
| 7 |
32881518 | Relative Quantitation of Beta-Amyloid Peptide Isomers with Simultaneous Isomerization of Multiple Aspartic Acid Residues by Matrix Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry. | 2020 Jan 2 |
1 |
| 8 |
33052996 | On the propagation of the OH radical produced by Cu-amyloid beta peptide model complexes. Insight from molecular modelling. | 2020 Nov 1 |
1 |
| 9 |
31482121 | Spontaneous Isomerization of Long-Lived Proteins Provides a Molecular Mechanism for the Lysosomal Failure Observed in Alzheimer's Disease. | 2019 Aug 28 |
2 |
| 10 |
26175157 | Mesotrypsin Has Evolved Four Unique Residues to Cleave Trypsin Inhibitors as Substrates. | 2015 Aug 28 |
1 |
| 11 |
24617810 | Turn plasticity distinguishes different modes of amyloid-β aggregation. | 2014 Apr 2 |
1 |
| 12 |
24803226 | Focusing the amyloid cascade hypothesis on N-truncated Abeta peptides as drug targets against Alzheimer's disease. | 2014 |
1 |
| 13 |
25178721 | Sulforaphane interaction with amyloid beta 1-40 peptide studied by electrospray ionization mass spectrometry. | 2014 Oct 30 |
1 |
| 14 |
23291379 | Ethanol reduces amyloid aggregation in vitro and prevents toxicity in cell lines. | 2013 Jan |
1 |
| 15 |
23344882 | A quantitative analysis of spontaneous isoaspartate formation from N-terminal asparaginyl and aspartyl residues. | 2013 Apr |
1 |
| 16 |
23484851 | Effect of sequence on the ionization behavior of a series of amphiphilic polypeptides. | 2013 Apr 9 |
3 |
| 17 |
23660814 | Molecular dynamics simulation and molecular docking studies of Angiotensin converting enzyme with inhibitor lisinopril and amyloid Beta Peptide. | 2013 Jun |
2 |
| 18 |
23888782 | [Identification of the minimal zinc-binding center in natural isoforms of amyloid-beta domain 1-16 using ESI-MS]. | 2013 May-Jun |
1 |
| 19 |
23904252 | In silico and in vitro studies to elucidate the role of Cu2+ and galanthamine as the limiting step in the amyloid beta (1-42) fibrillation process. | 2013 Oct |
2 |
| 20 |
24028142 | Differential contribution of isoaspartate post-translational modifications to the fibrillization and toxic properties of amyloid β and the Asn23 Iowa mutation. | 2013 Dec 15 |
1 |
| 21 |
24383085 | Site-specific aspartic acid isomerization regulates self-assembly and neurotoxicity of amyloid-β. | 2013 Nov 15 |
1 |
| 22 |
21500352 | Amyloid precursor protein mutation E682K at the alternative β-secretase cleavage β'-site increases Aβ generation. | 2011 May |
2 |
| 23 |
21757705 | Evidence for an extended hydrogen bond network in the binding site of the nicotinic receptor: role of the vicinal disulfide of the alpha1 subunit. | 2011 Sep 16 |
1 |
| 24 |
22191059 | On the involvement of copper binding to the N-terminus of the amyloid Beta Peptide of Alzheimer's disease: a computational study on model systems. | 2011 |
1 |
| 25 |
20557062 | Exploring the surface charge on peptide-gold nanoparticle conjugates by force spectroscopy. | 2010 Jul 20 |
1 |
| 26 |
19402527 | [Effect of isomerization of aspartate-7 on the binding of copper (II) ion by the beta-amyloid peptide]. | 2009 Mar-Apr |
1 |
| 27 |
18085519 | The N-domain of angiotensin-converting enzyme specifically hydrolyzes the Arg-5-His-6 bond of Alzheimer's Abeta-(1-16) peptide and its isoAsp-7 analogue with different efficiency as evidenced by quantitative matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. | 2008 |
2 |
| 28 |
18599641 | The structure of the amyloid-beta peptide high-affinity copper II binding site in Alzheimer disease. | 2008 Oct |
1 |
| 29 |
17352478 | Role of aspartate-1 in Cu(II) binding to the amyloid-beta peptide of Alzheimer's disease. | 2007 Apr 4 |
1 |
| 30 |
17940047 | Familial Alzheimer's disease mutations alter the stability of the amyloid beta-protein monomer folding nucleus. | 2007 Oct 16 |
1 |
| 31 |
16301322 | Structural changes of region 1-16 of the Alzheimer disease amyloid beta-peptide upon zinc binding and in vitro aging. | 2006 Jan 27 |
1 |
| 32 |
15633197 | Switching of turn conformation in an aspartate anion peptide fragment by NH . . . O- hydrogen bonds. | 2005 |
1 |
| 33 |
15706615 | Hydrolysis of the amyloid beta-peptide (A beta) 1-40 between Asp23-Val24 produces non-aggregating fragments. An electrospray mass spectrometric study. | 2005 Feb |
1 |
| 34 |
16091285 | Effect of D-amino acids at Asp23 and Ser26 residues on the conformational preference of Abeta20-29 peptides. | 2005 Sep 30 |
1 |
| 35 |
16246054 | Expression and activity of beta-site amyloid precursor protein cleaving enzyme in Alzheimer's disease. | 2005 Nov |
2 |
| 36 |
12391606 | Isoaspartate formation at position 23 of amyloid beta peptide enhanced fibril formation and deposited onto senile plaques and vascular amyloids in Alzheimer's disease. | 2002 Nov 1 |
1 |
| 37 |
12391608 | In vivo conversion of racemized beta-amyloid ([D-Ser 26]A beta 1-40) to truncated and toxic fragments ([D-Ser 26]A beta 25-35/40) and fragment presence in the brains of Alzheimer's patients. | 2002 Nov 1 |
1 |
| 38 |
11580253 | Identification and characterization of key kinetic intermediates in amyloid beta-protein fibrillogenesis. | 2001 Oct 5 |
1 |
| 39 |
11604391 | Angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide (A beta ); retards A beta aggregation, deposition, fibril formation; and inhibits cytotoxicity. | 2001 Dec 21 |
2 |
| 40 |
11898552 | Amyloid metabolism and secretases in Alzheimer's disease. | 2001 Sep |
1 |
| 41 |
10652302 | The transmembrane aspartates in presenilin 1 and 2 are obligatory for gamma-secretase activity and amyloid beta-protein generation. | 2000 Feb 4 |
2 |
| 42 |
10783238 | Presenilin-1 differentially facilitates endoproteolysis of the beta-amyloid precursor protein and Notch. | 2000 Apr |
2 |
| 43 |
10922078 | Presenilin complexes with the C-terminal fragments of amyloid precursor protein at the sites of amyloid beta-protein generation. | 2000 Aug 1 |
3 |
| 44 |
11056541 | Glycine 384 is required for presenilin-1 function and is conserved in bacterial polytopic aspartyl proteases. | 2000 Nov |
2 |
| 45 |
10095028 | Immunohistochemical localization of amyloid beta-protein with amino-terminal aspartate in the cerebral cortex of patients with Alzheimer's disease. | 1999 Mar 27 |
1 |
| 46 |
10521267 | Zebrafish (Danio rerio) presenilin promotes aberrant amyloid beta-peptide production and requires a critical aspartate residue for its function in amyloidogenesis. | 1999 Oct 12 |
1 |
| 47 |
9600199 | N-terminal heterogeneity of parenchymal and cerebrovascular Abeta deposits. | 1998 Jan |
1 |
| 48 |
8632167 | Evaluation of cathepsins D and G and EC 3.4.24.15 as candidate beta-secretase proteases using peptide and amyloid precursor protein substrates. | 1996 Jun |
1 |
| 49 |
8738655 | The effects of aspartic acid-bond isomerization on in vitro properties of the amyloid beta-peptide as modeled with N-terminal decapeptide fragments. | 1996 Apr |
2 |
| 50 |
8755488 | Inhibition of amyloid beta-protein production in neural cells by the serine protease inhibitor AEBSF. | 1996 Jul |
1 |