Title : Zebrafish (Danio rerio) presenilin promotes aberrant amyloid beta-peptide production and requires a critical aspartate residue for its function in amyloidogenesis.

Pub. Date : 1999 Oct 12

PMID : 10521267






1 Functional Relationships(s)
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Protein Name
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1 Mutagenizing this critical aspartate residue abolishes endoproteolysis of zf-PS1 and inhibits Abeta secretion in human cells. Aspartic Acid amyloid beta precursor protein Homo sapiens