| 1 |
33060787 | Homogeneous single-label cGMP detection platform for the functional study of nitric oxide-sensitive (soluble) guanylyl cyclases and cGMP-specific phosphodiesterases. | 2020 Oct 15 |
2 |
| 2 |
31125564 | Therapeutic opportunities in colon cancer: Focus on phosphodiesterase inhibitors. | 2019 Aug 1 |
2 |
| 3 |
29604206 | From molecules to patients: exploring the therapeutic role of soluble guanylate cyclase stimulators. | 2018 Jun 27 |
1 |
| 4 |
27413196 | The role of cGMP and its signaling pathways in kidney disease. | 2016 Oct 1 |
5 |
| 5 |
28959341 | Expression of Recombinant Phosphodiesterases 3A and 3B Using Baculovirus Expression System. | 2016 Dec |
1 |
| 6 |
25843350 | A synthetic cGMP-sensitive gene switch providing Viagra(®)-controlled gene expression in mammalian cells and mice. | 2015 May |
1 |
| 7 |
26299804 | Suppression of β-catenin/TCF transcriptional activity and colon tumor cell growth by dual inhibition of PDE5 and 10. | 2015 Sep 29 |
1 |
| 8 |
26388264 | Interaction between phosphodiesterases in the regulation of the cardiac β-adrenergic pathway. | 2015 Nov |
3 |
| 9 |
25277835 | Synthesis and biological evaluation of novel pyridine derivatives as potential anticancer agents and phosphodiesterase-3 inhibitors. | 2014 Dec |
1 |
| 10 |
22383129 | Potential therapeutic applications of phosphodiesterase inhibition in prostate cancer. | 2013 Apr |
1 |
| 11 |
22261303 | Profiling of cAMP and cGMP phosphodiesterases in isolated ventricular cardiomyocytes from human hearts: comparison with rat and guinea pig. | 2012 Feb 27 |
1 |
| 12 |
21477871 | Phosphodiesterases and cardiac cGMP: evolving roles and controversies. | 2011 Jun |
1 |
| 13 |
21908708 | Restoring soluble guanylyl cyclase expression and function blocks the aggressive course of glioma. | 2011 Dec |
1 |
| 14 |
21962440 | The roles of cyclic nucleotide phosphodiesterases (PDEs) in steroidogenesis. | 2011 Dec |
2 |
| 15 |
20001559 | Targeting cancer with phosphodiesterase inhibitors. | 2010 Jan |
4 |
| 16 |
19089327 | Structural and biochemical aspects of tandem GAF domains. | 2009 |
1 |
| 17 |
18590734 | Cyclic nucleotide-specific phosphodiesterases of Plasmodium falciparum: PfPDEalpha, a non-essential cGMP-specific PDE that is an integral membrane protein. | 2008 Dec |
3 |
| 18 |
17376027 | Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling. | 2007 |
1 |
| 19 |
15988069 | Analysis of dimerization determinants of PDE6 catalytic subunits. | 2005 |
2 |
| 20 |
16123402 | Efficacy and selectivity of phosphodiesterase-targeted drugs in inhibiting photoreceptor phosphodiesterase (PDE6) in retinal photoreceptors. | 2005 Sep |
3 |
| 21 |
15633907 | [Cardiac rehabilitation and resuming sexual activity]. | 2004 Sep |
1 |
| 22 |
11171061 | Identification and characterization of DdPDE3, a cGMP-selective phosphodiesterase from Dictyostelium. | 2001 Feb 1 |
1 |
| 23 |
10051534 | Potency and mechanism of action of E4021, a type 5 phosphodiesterase isozyme-selective inhibitor, on the photoreceptor phosphodiesterase depend on the state of activation of the enzyme. | 1999 Mar |
2 |
| 24 |
10373499 | cGMP binding to noncatalytic sites on mammalian rod photoreceptor phosphodiesterase is regulated by binding of its gamma and delta subunits. | 1999 Jun 25 |
12 |
| 25 |
9500855 | Antisense inhibition of phosphodiesterase expression. | 1998 Jan |
1 |
| 26 |
9618252 | Isolation and characterization of PDE8A, a novel human cAMP-specific phosphodiesterase. | 1998 May 29 |
1 |
| 27 |
9357856 | Regulation of cGMP by soluble and particulate guanylyl cyclases in cultured human airway smooth muscle. | 1997 Oct |
6 |
| 28 |
8762090 | Evidence that cyclic AMP phosphodiesterase inhibitors suppress TNF alpha generation from human monocytes by interacting with a 'low-affinity' phosphodiesterase 4 conformer. | 1996 Jun |
1 |
| 29 |
8825382 | Effects of maturation on cyclic GMP metabolism in ovine carotid arteries. | 1996 Jan |
2 |
| 30 |
7540392 | Stimulation of placental prorenin secretion by selective inhibition of cyclic nucleotide phosphodiesterases. | 1995 May 26 |
1 |
| 31 |
7712010 | Further analysis of the mechanisms underlying the tracheal relaxant action of SCA40. | 1995 Jan |
1 |
| 32 |
7789494 | Cyclic nucleotides and phosphodiesterases and airway function. | 1995 Mar |
1 |
| 33 |
7952568 | Potentiation of nonadrenergic noncholinergic relaxation of human isolated bronchus by selective inhibitors of phosphodiesterase isozymes. | 1994 Nov |
1 |
| 34 |
8038108 | Cyclic GMP and regulation of cyclic nucleotide hydrolysis. | 1994 |
5 |
| 35 |
8075643 | Heterozygous missense mutation in the rod cGMP phosphodiesterase beta-subunit gene in autosomal dominant stationary night blindness. | 1994 May |
1 |
| 36 |
8387599 | Synthesis and phosphodiesterase activity of carboxylic acid mimetics of cyclic guanosine 3',5'-monophosphate. | 1993 Apr 30 |
1 |
| 37 |
8393348 | [Ca2+-calmodulin-activated cyclic nucleotide phosphodiesterase from the soluble fraction of the human brain: Kinetic properties and the effect of the antidepressant pyrazidol and its nitro analog on the enzyme]. | 1993 May |
3 |
| 38 |
2535910 | Biochemical aspects of inhibition of cardiovascular low (Km) cyclic adenosine monophosphate phosphodiesterase. | 1989 Jan 3 |
1 |
| 39 |
2535936 | Correlation between selective inhibition of the cyclic nucleotide phosphodiesterases and the contractile activity in human pregnant myometrium near term. | 1989 Jan 1 |
1 |
| 40 |
2835985 | Properties and content of cyclic nucleotide phosphodiesterase in photoreceptor outer segments of ground squirrel retina. | 1988 Jun 13 |
3 |
| 41 |
6326517 | Cyclic nucleotide derivatives as probes of phosphodiesterase catalytic and regulatory sites. | 1984 |
7 |
| 42 |
6305023 | Gain, speed and sensitivity of GTP binding vs PDE activation in visual excitation. | 1982 |
1 |