NAD

lactate dehydrogenase A ; Homo sapiens







28 Article(s)
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1 34725423 Identification of the first highly selective inhibitor of human lactate dehydrogenase B. 2021 Nov 1 2
2 32647171 LDHA-mediated ROS generation in chondrocytes is a potential therapeutic target for osteoarthritis. 2020 Jul 9 1
3 31035592 Unappreciated Role of LDHA and LDHB to Control Apoptosis and Autophagy in Tumor Cells. 2019 Apr 27 4
4 29194006 Retention of functional characteristics of glutathione-S-transferase and lactate dehydrogenase-A in fusion protein. 2018 Feb 7 2
5 30209241 Targeting the Warburg effect via LDHA inhibition engages ATF4 signaling for cancer cell survival. 2018 Oct 15 2
6 28525376 Exploiting ROS and metabolic differences to kill cisplatin resistant lung cancer. 2017 Jul 25 1
7 28950656 Oxamate potentiates taxol chemotherapeutic efficacy in experimentally-induced solid ehrlich carcinoma (SEC) in mice. 2017 Nov 4
8 25664730 Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms. 2015 Feb 4
9 25918543 1,2,3,4,6-Penta-O-galloylglucose within Galla Chinensis Inhibits Human LDH-A and Attenuates Cell Proliferation in MDA-MB-231 Breast Cancer Cells. 2015 2
10 26085945 Search for Human Lactate Dehydrogenase A Inhibitors Using Structure-Based Modeling. 2015 Apr-Jun 2
11 26114812 Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors. 2015 Aug 28 2
12 26246802 Metabolic Consequences of LDHA inhibition by Epigallocatechin Gallate and Oxamate in MIA PaCa-2 Pancreatic Cancer Cells. 2015 Feb 6
13 24816116 Structural characterization of the apo form and NADH binary complex of human lactate dehydrogenase. 2014 May 2
14 24819061 Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53-independent pathways. 2014 May 12 12
15 25037916 Identification of substituted 3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase. 2014 Aug 15 2
16 23237800 Galloflavin prevents the binding of lactate dehydrogenase A to single stranded DNA and inhibits RNA synthesis in cultured cells. 2013 Jan 11 3
17 23307072 Intracellular NAD(H) levels control motility and invasion of glioma cells. 2013 Jun 1
18 23460848 The proteome of human liver peroxisomes: identification of five new peroxisomal constituents by a label-free quantitative proteomics survey. 2013 1
19 23628333 Identification of substituted 2-thio-6-oxo-1,6-dihydropyrimidines as inhibitors of human lactate dehydrogenase. 2013 Jun 1 1
20 24280423 Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells. 2013 Sep 6 1
21 22052811 Galloflavin (CAS 568-80-9): a novel inhibitor of lactate dehydrogenase. 2012 Feb 6 1
22 22417091 Design and synthesis of novel lactate dehydrogenase A inhibitors by fragment-based lead generation. 2012 Apr 12 2
23 21332213 Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells. 2011 Mar 24 1
24 21969607 Tyrosine phosphorylation of lactate dehydrogenase A is important for NADH/NAD(+) redox homeostasis in cancer cells. 2011 Dec 9
25 17555402 Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1. 2007 Jul 1 2
26 16198644 A preliminary account of the properties of recombinant human Glyoxylate reductase (GRHPR), LDHA and LDHB with glyoxylate, and their potential roles in its metabolism. 2005 Dec 1 1
27 7630349 Characterization of the glycolysis in lactate dehydrogenase-A deficiency. 1995 Aug 1
28 7986093 Effect of tubulin on the activity of the muscle isoenzyme of lactate dehydrogenase. 1994 Dec 5