Title : LDHA-mediated ROS generation in chondrocytes is a potential therapeutic target for osteoarthritis.

Pub. Date : 2020 Jul 9

PMID : 32647171






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 LDHA binds to NADH and promotes reactive oxygen species (ROS) to induce catabolic changes through stabilization of IkappaB-zeta, a critical pro-inflammatory mediator in chondrocytes. NAD lactate dehydrogenase A Homo sapiens