Title : Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1.

Pub. Date : 2007 Jul 1

PMID : 17555402






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In combination with the hypoxia-induced expression of LDHA (lactate dehydrogenase A), which converts pyruvate into lactate, PDK1 reduces the delivery of acetyl-CoA to the tricarboxylic acid cycle, thus reducing the levels of NADH and FADH2 delivered to the electron-transport chain. NAD lactate dehydrogenase A Homo sapiens
2 In combination with the hypoxia-induced expression of LDHA (lactate dehydrogenase A), which converts pyruvate into lactate, PDK1 reduces the delivery of acetyl-CoA to the tricarboxylic acid cycle, thus reducing the levels of NADH and FADH2 delivered to the electron-transport chain. NAD lactate dehydrogenase A Homo sapiens