Title : Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells.

Pub. Date : 2011 Mar 24

PMID : 21332213

1 Functional Relationships(s)
Compound Name
Protein Name
1 We have discovered new and efficient N-hydroxyindole-based inhibitors of LDH-A, which are isoform-selective (over LDH-B) and competitive with both the substrate (pyruvate) and the cofactor (NADH). NAD lactate dehydrogenase A Homo sapiens