| 1 |
35619689 | Topical Simvastatin Improves Lesions of Diffuse Normolipemic Plane Xanthoma by Inhibiting Foam Cell Pyroptosis. | 2022 |
3 |
| 2 |
35624221 | Polyploid giant cancer cells are dependent on cholesterol for progeny formation through amitotic division. | 2022 May 27 |
1 |
| 3 |
33554328 | Simvastatin in vitiligo: an update with recent review of the literature. | 2021 Oct |
1 |
| 4 |
33992804 | Targeting cholesterol biosynthesis promotes anti-tumor immunity by inhibiting long noncoding RNA SNHG29-mediated YAP activation. | 2021 Oct 6 |
2 |
| 5 |
34425670 | A Novel Splice Site Variant in the LDLRAP1 Gene Causes Familial Hypercholesterolemia | 2021 Sep 1 |
1 |
| 6 |
34627266 | Simvastatin induced ferroptosis for triple-negative breast cancer therapy. | 2021 Oct 9 |
3 |
| 7 |
34680049 | HMG-CoA Reductase Inhibitor, Simvastatin Is Effective in Decreasing Degree of Myocarditis by Inhibiting Metalloproteinases Activation. | 2021 Sep 28 |
1 |
| 8 |
31915059 | Statin-induced anti-HMGCR myopathy: successful therapeutic strategies for corticosteroid-free remission in 55 patients. | 2020 Jan 8 |
3 |
| 9 |
32042518 | Self-reported Morisky Eight-item Medication Adherence Scale for Statins Concords with the Pill Count Method and Correlates with Serum Lipid Profile Parameters and Serum HMGCoA Reductase Levels. | 2020 Jan 2 |
1 |
| 10 |
32068819 | Association Between Genetically Proxied Inhibition of HMG-CoA Reductase and Epithelial Ovarian Cancer. | 2020 Feb 18 |
2 |
| 11 |
30255302 | Simvastatin Therapy and Bronchoalveolar Lavage Fluid Biomarkers in Chronic Obstructive Pulmonary Disease. | 2019 |
1 |
| 12 |
30833076 | Kruppel-like factor 2 mediated anti-proliferative and anti-metastasis effects of simvastatin in p53 mutant colon cancer. | 2019 Apr 16 |
1 |
| 13 |
31737505 | Current perspectives on statins as potential anti-cancer therapeutics: clinical outcomes and underlying molecular mechanisms. | 2019 Oct |
2 |
| 14 |
31791994 | Statin-induced anti-HMGCR antibody-related immune-mediated necrotising myositis achieving complete remission with rituximab. | 2019 Dec 1 |
1 |
| 15 |
31861911 | Statin-Related Myotoxicity: A Comprehensive Review of Pharmacokinetic, Pharmacogenomic and Muscle Components. | 2019 Dec 20 |
1 |
| 16 |
30015955 | Low‑frequency ultrasound and microbubbles combined with simvastatin promote the apoptosis of MCF‑7 cells by affecting the LATS1/YAP/RHAMM pathway. | 2018 Sep |
1 |
| 17 |
30089652 | Inhibition of cholesterol biosynthesis overcomes enzalutamide resistance in castration-resistant prostate cancer (CRPC). | 2018 Sep 14 |
1 |
| 18 |
30106444 | Inhibition of YAP reverses primary resistance to EGFR inhibitors in colorectal cancer cells. | 2018 Oct |
1 |
| 19 |
30563555 | Prevention of post-operative complications by using a HMG-CoA reductase inhibitor in patients undergoing one-lung ventilation for non-cardiac surgery: study protocol for a randomised controlled trial. | 2018 Dec 18 |
1 |
| 20 |
27513191 | A placebo-controlled trial of simvastatin therapy in Smith-Lemli-Opitz syndrome. | 2017 Mar |
2 |
| 21 |
28928655 | Effects of Simvastatin Beyond Dyslipidemia: Exploring Its Antinociceptive Action in an Animal Model of Complex Regional Pain Syndrome-Type I. | 2017 |
1 |
| 22 |
28930754 | Simvastatin, a Novel Stimulator of Eryptosis, the Suicidal Erythrocyte Death. | 2017 |
1 |
| 23 |
32095453 | Comparative pharmacokinetic and tolerability evaluation of two simvastatin 20 mg formulations in healthy Korean male volunteers. | 2017 Mar |
1 |
| 24 |
26319048 | In vitro and in vivo downregulation of the ATP binding cassette transporter B1 by the HMG-CoA reductase inhibitor simvastatin. | 2016 Jan |
1 |
| 25 |
26502771 | Voriconazole-Induced Hepatitis via Simvastatin- and Lansoprazole-Mediated Drug Interactions: A Case Report and Review of the Literature. | 2016 Jan |
1 |
| 26 |
26761203 | Simvastatin Ameliorates Matrix Stiffness-Mediated Endothelial Monolayer Disruption. | 2016 |
1 |
| 27 |
27042994 | Simvastatin Reduces Cancerogenic Potential of Renal Cancer Cells via Geranylgeranyl Pyrophosphate and Mevalonate Pathway. | 2016 |
1 |
| 28 |
27335167 | Chamber-specific differences in human cardiac fibroblast proliferation and responsiveness toward simvastatin. | 2016 Aug 1 |
1 |
| 29 |
27470565 | Simvastatin inhibits glucose uptake activity and GLUT4 translocation through suppression of the IR/IRS-1/Akt signaling in C2C12 myotubes. | 2016 Oct |
1 |
| 30 |
25453767 | HMG-CoA reductase inhibitor rosuvastatin improves abnormal brain electrical activity via mechanisms involving eNOS. | 2015 Jan 22 |
1 |
| 31 |
25901147 | Galactosylated albumin nanoparticles of simvastatin. | 2015 Spring |
1 |
| 32 |
25982544 | Evaluating early administration of the hydroxymethylglutaryl-CoA reductase inhibitor simvastatin in the prevention and treatment of delirium in critically ill ventilated patients (MoDUS trial): study protocol for a randomized controlled trial. | 2015 May 16 |
1 |
| 33 |
26277021 | Synergistic Effect of Simvastatin Plus Radiation in Gastric Cancer and Colorectal Cancer: Implications of BIRC5 and Connective Tissue Growth Factor. | 2015 Oct 1 |
1 |
| 34 |
24666612 | Effect of simvastatin on castration-resistant prostate cancer cells. | 2014 Mar 26 |
2 |
| 35 |
24806822 | Novel simvastatin inhalation formulation and characterisation. | 2014 Aug |
1 |
| 36 |
25122066 | Synergistic simvastatin and metformin combination chemotherapy for osseous metastatic castration-resistant prostate cancer. | 2014 Oct |
2 |
| 37 |
25311809 | Inhibition of protein geranylgeranylation specifically interferes with CD40-dependent B cell activation, resulting in a reduced capacity to induce T cell immunity. | 2014 Nov 15 |
1 |
| 38 |
23256625 | Evaluation of drug interactions of GSK1292263 (a GPR119 agonist) with statins: from in vitro data to clinical study design. | 2013 Jun |
1 |
| 39 |
23386644 | Resveratrol potentiates effect of simvastatin on inhibition of mevalonate pathway in human endometrial stromal cells. | 2013 Mar |
3 |
| 40 |
23541442 | Interleukin-18 enhances IL-18R/Nox1 binding, and mediates TRAF3IP2-dependent smooth muscle cell migration. Inhibition by simvastatin. | 2013 Jun |
1 |
| 41 |
23817018 | Simvastatin attenuates TGF-β1-induced epithelial-mesenchymal transition in human alveolar epithelial cells. | 2013 |
2 |
| 42 |
23846804 | HMG-CoA reductase inhibitors, simvastatin and atorvastatin, downregulate ABCG1-mediated cholesterol efflux in human macrophages. | 2013 Jul |
1 |
| 43 |
21871960 | Inhibition of AMPK-dependent autophagy enhances in vitro antiglioma effect of simvastatin. | 2012 Jan |
1 |
| 44 |
22541079 | [Effects of simvastatin on PI3K/AKT signaling pathway in human acute monocytic leukemia cell line SHI-1]. | 2012 Apr |
1 |
| 45 |
22658637 | TNF-α modulates statin effects on secretion and expression of MCP-1, PAI-1 and adiponectin in 3T3-L1 differentiated adipocytes. | 2012 Oct |
1 |
| 46 |
22761797 | The importance of LDL and cholesterol metabolism for prostate epithelial cell growth. | 2012 |
1 |
| 47 |
22985805 | Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in acute lung injury to reduce pulmonary dysfunction (HARP-2) trial: study protocol for a randomized controlled trial. | 2012 Sep 17 |
3 |
| 48 |
29403775 | Validated LC-MS/MS method for simultaneous determination of SIM and its acid form in human plasma and cell lysate: Pharmacokinetic application. | 2012 Dec |
2 |
| 49 |
20467885 | Simvastatin enhances irinotecan-induced apoptosis in human non-small cell lung cancer cells by inhibition of proteasome activity. | 2011 Oct |
2 |
| 50 |
20473500 | HMG-CoA reductase inhibitor simvastatin suppresses Toll-like receptor 2 ligand-induced activation of nuclear factor kappa B by preventing RhoA activation in monocytes from rheumatoid arthritis patients. | 2011 Nov |
3 |