Title : Simvastatin attenuates TGF-β1-induced epithelial-mesenchymal transition in human alveolar epithelial cells.

Pub. Date : 2013

PMID : 23817018






2 Functional Relationships(s)
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1 Simvastatin (Sim), a 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase inhibitor, has been previously reported to inhibit EMT in human proximal tubular epithelial cells and porcine lens epithelial cells and to suppress Smad2/3 phosphorylation in animal models. Simvastatin 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens
2 Simvastatin (Sim), a 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase inhibitor, has been previously reported to inhibit EMT in human proximal tubular epithelial cells and porcine lens epithelial cells and to suppress Smad2/3 phosphorylation in animal models. Simvastatin 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens