Pub. Date : 2013 Mar
PMID : 23386644
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Simvastatin inhibited cholesterol biosynthesis and enzyme activity but increased HMGCR mRNA and protein expression. | Simvastatin | 3-hydroxy-3-methylglutaryl-CoA reductase | Homo sapiens |
| 2 | Resveratrol potentiated the inhibitory effects of simvastatin on cholesterol biosynthesis and HMGCR enzyme activity and abrogated the stimulatory effects of simvastatin on HMGCR mRNA transcripts and protein expression. | Simvastatin | 3-hydroxy-3-methylglutaryl-CoA reductase | Homo sapiens |
| 3 | Resveratrol potentiated the inhibitory effects of simvastatin on cholesterol biosynthesis and HMGCR enzyme activity and abrogated the stimulatory effects of simvastatin on HMGCR mRNA transcripts and protein expression. | Simvastatin | 3-hydroxy-3-methylglutaryl-CoA reductase | Homo sapiens |