histone deacetylase 2 ; Homo sapiens






349 Article(s)
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301 32335896 Restoration of HDAC2 and Nrf2 by andrographolide overcomes corticosteroid resistance in chronic obstructive pulmonary disease. Br J Pharmacol 2020 Aug 4
302 32367603 Histone Deacetylase 2 (HDAC2) Inhibitors Containing Boron. Chembiochem 2020 Oct 1 10
303 32469696 Role of P-gp and HDAC2 and their Reciprocal Relationship in Uncontrolled Asthma. Curr Pharm Biotechnol 2021 2
304 32550884 Effects of icariin on cell injury and glucocorticoid resistance in BEAS-2B cells exposed to cigarette smoke extract. Exp Ther Med 2020 Jul 1
305 32592040 Imaging assisted evaluation of antitumor efficacy of a new histone deacetylase inhibitor in the castration-resistant prostate cancer. Eur J Nucl Med Mol Imaging 2021 Jan 1
306 32599665 Histone deacetylase inhibition prevents the growth of primary and metastatic osteosarcoma. Int J Cancer 2020 Nov 15 1
307 32698523 PCAF Involvement in Lamin A/C-HDAC2 Interplay during the Early Phase of Muscle Differentiation. Cells 2020 Jul 20 3
308 32774482 miR-489-3p inhibits proliferation and migration of bladder cancer cells through downregulation of histone deacetylase 2. Oncol Lett 2020 Oct 1
309 32818949 Antenatal N-acetylcysteine to improve outcomes of premature infants with intra-amniotic infection and inflammation (Triple I): randomized clinical trial. Pediatr Res 2021 Jan 3
310 32913546 Nintedanib ameliorates tracheal stenosis by activating HDAC2 and suppressing IL-8 and VEGF in rabbit. Am J Transl Res 2020 5
311 33010345 The Spinal Extracellular Matrix Modulates a Multi-level Protein Net and Epigenetic Inducers Following Peripheral Nerve Injury. Neuroscience 2020 Dec 15 1
312 33105741 The Budesonide-Hydroxypropyl-β-Cyclodextrin Complex Attenuates ROS Generation, IL-8 Release and Cell Death Induced by Oxidant and Inflammatory Stress. Study on A549 and A-THP-1 Cells. Molecules 2020 Oct 22 1
313 33117625 Epigallocatechin gallate inhibits HeLa cells by modulation of epigenetics and signaling pathways. 3 Biotech 2020 Nov 1
314 33196720 Implantable HDAC-inhibiting chemotherapeutics derived from hydrophobic amino acids for localized anticancer therapy. Biomater Sci 2021 Jan 5 4
315 33216461 Increased transcription of TSPO, HDAC2, and HDAC6 in the amygdala of males with alcohol use disorder. Brain Behav 2021 Feb 1
316 33431796 Histone deacetylase 2 regulates ULK1 mediated pyroptosis during acute liver failure by the K68 acetylation site. Cell Death Dis 2021 Jan 11 3
317 33558457 Ketogenic diets inhibit mitochondrial biogenesis and induce cardiac fibrosis. Signal Transduct Target Ther 2021 Feb 9 2
318 33608482 Leptin-elicited PBX3 confers letrozole resistance in breast cancer. Endocr Relat Cancer 2021 Feb 1 1
319 33652374 Theophylline alleviates gentamicin-induced cytotoxicity to sensory hair cells by maintaining HDAC2 expression. Acta Histochem 2021 Apr 10
320 33668324 FOXC1 Downregulates Nanog Expression by Recruiting HDAC2 to Its Promoter in F9 Cells Treated by Retinoic Acid. Int J Mol Sci 2021 Feb 24 1
321 33797132 Green tea polyphenols inhibit malignant melanoma progression via regulating circ_MITF/miR-30e-3p/HDAC2 axis. Biotechnol Appl Biochem 2022 Apr 1
322 33966346 Delineating binding potential, stability of Sulforaphane-N-acetyl-cysteine in the active site of histone deacetylase 2 and testing its cytotoxicity against distinct cancer lines through stringent molecular dynamics, DFT and cell-based assays. Chem Biol Drug Des 2021 Sep 7
323 34029327 Low-dose theophylline in addition to ICS therapy in COPD patients: A systematic review and meta-analysis. PLoS One 2021 4
324 34069280 The Selective Histone Deacetylase Inhibitor MI192 Enhances the Osteogenic Differentiation Efficacy of Human Dental Pulp Stromal Cells. Int J Mol Sci 2021 May 14 2
325 34082508 Sulforaphane Ameliorates Diabetes-Induced Renal Fibrosis through Epigenetic Up-Regulation of BMP-7. Diabetes Metab J 2021 Nov 1
326 34099674 Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites. Nat Commun 2021 Jun 7 1
327 34105828 The miR-455-3p/HDAC2 axis plays a pivotal role in the progression and reversal of liver fibrosis and is regulated by epigenetics. FASEB J 2021 Jul 1
328 34111829 A first-in-class anticancer dual HDAC2/FAK inhibitors bearing hydroxamates/benzamides capped by pyridinyl-1,2,4-triazoles. Eur J Med Chem 2021 Oct 15 5
329 34339909 MI192 induced epigenetic reprogramming enhances the therapeutic efficacy of human bone marrows stromal cells for bone regeneration. Bone 2021 Dec 1
330 34369509 Rational design of selective HDAC2 inhibitors for liver cancer treatment: computational insights into the selectivity mechanism through molecular dynamics simulations and QM/MM calculations. Phys Chem Chem Phys 2021 Aug 28 2
331 34395436 Integrated Chromatin Accessibility and Transcriptome Landscapes of Doxorubicin-Resistant Breast Cancer Cells. Front Cell Dev Biol 2021 1
332 34407000 Optimal Sampling Strategy and Threshold of Serum Vancomycin Concentration in Elderly Japanese Patients Undergoing High-Flux Hemodialysis. Ther Drug Monit 2022 Jun 1 1
333 34478690 Effects of intranasal azithromycin on features of cigarette smoke-induced lung inflammation. Eur J Pharmacol 2022 Jan 15 1
334 34509167 Design, synthesis and biological evaluation of novel hybrids targeting mTOR and HDACs for potential treatment of hepatocellular carcinoma. Eur J Med Chem 2021 Dec 5 3
335 34604061 Axitinib and HDAC Inhibitors Interact to Kill Sarcoma Cells. Front Oncol 2021 1
336 34974051 Nonylphenol regulates TL1A through the AhR/HDAC2/HNF4α pathway in endothelial cells to promote the angiogenesis of colorectal cancer. Toxicol Appl Pharmacol 2022 Feb 1 1
337 34979835 Applying comparative molecular modelling techniques on diverse hydroxamate-based HDAC2 inhibitors: an attempt to identify promising structural features for potent HDAC2 inhibition. SAR QSAR Environ Res 2022 Jan 4
338 35260183 miR-3189-targeted GLUT3 repression by HDAC2 knockdown inhibits glioblastoma tumorigenesis through regulating glucose metabolism and proliferation. J Exp Clin Cancer Res 2022 Mar 8 2
339 35303413 MicroRNA-122-5p prevents proliferation and promotes apoptosis of hepatic stellate cells by suppressing the cellular-Abelsongene/histone deacetylases 2 pathway. Hum Exp Toxicol 2022 Jan-Dec 1
340 35337122 Development and Biological Evaluation of the First Highly Potent and Specific Benzamide-Based Radiotracer [<sup>18</sup>F]BA3 for Imaging of Histone Deacetylases 1 and 2 in Brain. Pharmaceuticals (Basel) 2022 Mar 8 1
341 35362831 Bone tissue engineering using 3D silk scaffolds and human dental pulp stromal cells epigenetic reprogrammed with the selective histone deacetylase inhibitor MI192. Cell Tissue Res 2022 Jun 1
342 35403781 Epithelial-mesenchymal transition and cancer stem cells: A route to acquired cisplatin resistance through epigenetics in HNSCC. Oral Dis 2022 Apr 11 1
343 35411221 Antibiotic heliomycin and its water-soluble 4-aminomethylated derivative provoke cell death in T24 bladder cancer cells by targeting sirtuin 1 (SIRT1). Am J Cancer Res 2022 7
344 35417530 Induction of Synthetic Lethality by Activation of Mitochondrial ClpP and Inhibition of HDAC1/2 in Glioblastoma. Clin Cancer Res 2022 May 2 1
345 35466223 GelMA Hydrogel Reinforced with 3D Printed PEGT/PBT Scaffolds for Supporting Epigenetically-Activated Human Bone Marrow Stromal Cells for Bone Repair. J Funct Biomater 2022 Apr 10 1
346 35512065 Design, synthesis, and biological evaluation of histone deacetylase inhibitor with novel salicylamide zinc binding group. Medicine (Baltimore) 2022 Apr 29 1
347 35535951 Mechanistic insights of key host proteins and potential repurposed inhibitors regulating SARS-CoV-2 pathway. J Comput Chem 2022 Jul 5 4
348 35608750 The epigenetic modifier HDAC2 and the checkpoint kinase ATM determine the responses of microsatellite instable colorectal cancer cells to 5-fluorouracil. Cell Biol Toxicol 2022 May 24 5
349 35611803 Silencing of lncRNA CRNDE attenuates nonsmall-cell lung cancer progression by mediating the miR-455-3p/HDAC2 axis. Kaohsiung J Med Sci 2022 May 25 1