| Protein Name | histone deacetylase 2 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 3066 |
| Gene Symbol | HDAC2 |
| UniProt | Q92769 (HDAC2_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
287
Total Number of Articles : 349 |
Description |
histone deacetylase 2 |
| Gene Summary |
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010] |
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