Title : Histone deacetylase inhibition prevents the growth of primary and metastatic osteosarcoma.

Pub. Date : 2020 Nov 15

PMID : 32599665






1 Functional Relationships(s)
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1 Mechanistically, the efficacy of panobinostat was linked to high expression of HDAC1 and HDAC2 in osteosarcoma, and silencing of HDAC1 and 2 greatly reduced osteosarcoma growth in vitro. Panobinostat histone deacetylase 2 Homo sapiens