Title : Leptin-elicited PBX3 confers letrozole resistance in breast cancer.

Pub. Date : 2021 Feb 1

PMID : 33608482






1 Functional Relationships(s)
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1 By profiling BCa cells with ectopic PBX3 expression, we revealed that PBX3 conferred letrozole resistance via transactivation of the FGFR1 signaling, and this molecular event must coordinate a synergistic transcription activation programs through interacting with MTA1-HDAC2 (metastasis associated 1-histone deacetylase 2) complex. Letrozole histone deacetylase 2 Homo sapiens