Pub. Date : 2021 Jun 7
PMID : 34099674
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To test our approach using a well characterized model system, we design cyclic peptides that inhibit histone deacetylases 2 and 6 (HDAC2 and HDAC6) with enhanced potency compared to the original anchor (IC50 values of 9.1 and 4.4 nM for the best binders compared to 5.4 and 0.6 microM for the anchor, respectively). | Peptides, Cyclic | histone deacetylase 2 | Homo sapiens |