8-oxoguanine DNA-glycosylase 1 ; Mus musculus






166 Article(s)
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1 9197244 A mammalian DNA repair enzyme that excises oxidatively damaged guanines maps to a locus frequently lost in lung cancer. Curr Biol 1997 Jun 1 3
2 9207108 Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase. Proc Natl Acad Sci U S A 1997 Jul 8 7
3 9434942 Genomic structure and chromosomal localization of the mouse Ogg1 gene that is involved in the repair of 8-hydroxyguanine in DNA damage. Mamm Genome 1998 Jan 3
4 10098454 Excision repair of 8-hydroxyguanine in mammalian cells: the mouse Ogg1 protein as a model. Free Radic Res 1998 Dec 5
5 10515589 Thermolabile 8-hydroxyguanine DNA glycosylase with low activity in senescence-accelerated mice due to a single-base mutation. Free Radic Biol Med 1999 Oct 7
6 10693941 Up-regulation of base excision repair activity for 8-hydroxy-2'-deoxyguanosine in the mouse brain after forebrain ischemia-reperfusion. J Neurochem 2000 Mar 10
7 10725358 Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice. Proc Natl Acad Sci U S A 2000 Apr 11 1
8 10884383 Substrate specificity and reaction mechanism of murine 8-oxoguanine-DNA glycosylase. J Biol Chem 2000 Sep 15 2
9 10890888 Transcription coupled repair of 8-oxoguanine in murine cells: the ogg1 protein is required for repair in nontranscribed sequences but not in transcribed sequences. Proc Natl Acad Sci U S A 2000 Jul 18 3
10 11431349 Retrovirus-mediated expression of the base excision repair proteins, formamidopyrimidine DNA glycosylase or human oxoguanine DNA glycosylase, protects hematopoietic cells from N,N',N"-triethylenethiophosphoramide (thioTEPA)-induced toxicity in vitro and in vivo. Cancer Res 2001 Jul 1 1
11 11454679 Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice. Cancer Res 2001 Jul 15 12
12 11532868 Age-related and tissue-specific accumulation of oxidative DNA base damage in 7,8-dihydro-8-oxoguanine-DNA glycosylase (Ogg1) deficient mice. Carcinogenesis 2001 Sep 2
13 11978483 Involvement of mammalian OGG1(MMH) in excision of the 8-hydroxyguanine residue in DNA. Free Radic Biol Med 2002 May 1 1
14 12017477 Modulation of base excision repair alters cellular sensitivity to UVA1 but not to UVB1. Photochem Photobiol 2002 May 1
15 12106825 Effects of diethylmaleate on DNA damage and repair in the mouse brain. Free Radic Biol Med 2002 Jul 15 3
16 12447686 A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage. Oncogene 2002 Nov 28 1
17 12507922 High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress. Carcinogenesis 2002 Dec 13
18 12509288 Inactivation of mammalian 8-oxoguanine-DNA glycosylase by cadmium(II): implications for cadmium genotoxicity. DNA Repair (Amst) 2002 Aug 6 11
19 12531013 Sorting the consequences of ionizing radiation: processing of 8-oxoguanine/abasic site lesions. DNA Repair (Amst) 2002 Dec 5 1
20 12644468 Mammalian 8-oxoguanine DNA glycosylase 1 incises 8-oxoadenine opposite cytosine in nuclei and mitochondria, while a different glycosylase incises 8-oxoadenine opposite guanine in nuclei. J Biol Chem 2003 May 23 14
21 12691525 Strain-specific differences in the expression and activity of Ogg1 in the CNS. Gene Expr 2003 3
22 12759433 Normal somatic hypermutation of Ig genes in the absence of 8-hydroxyguanine-DNA glycosylase. J Immunol 2003 Jun 1 2
23 12819227 Compromised incision of oxidized pyrimidines in liver mitochondria of mice deficient in NTH1 and OGG1 glycosylases. J Biol Chem 2003 Sep 5 1
24 12874039 Cell proliferation in liver of Mmh/Ogg1-deficient mice enhances mutation frequency because of the presence of 8-hydroxyguanine in DNA. Cancer Res 2003 Jul 15 7
25 14642563 Immunofluorescent localization of the murine 8-oxoguanine DNA glycosylase (mOGG1) in cells growing under normal and nutrient deprivation conditions. DNA Repair (Amst) 2003 Dec 9 1
26 14965360 Detection of a smaller, 32-kDa 8-oxoguanine DNA glycosylase 1 in 3'-methyl-4-dimethylamino-azobenzene-treated mouse liver. Cancer Sci 2004 Feb 1
27 15126047 Single extraction protocol for the analysis of 8-hydroxy-2'-deoxyguanosine (oxo8dG) and the associated activity of 8-oxoguanine DNA glycosylase. J Neurosci Methods 2004 Jun 15 2
28 15199168 MUTYH prevents OGG1 or APEX1 from inappropriately processing its substrate or reaction product with its C-terminal domain. Nucleic Acids Res 2004 1
29 15231648 Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumor-prone mice defective in both the Myh and Ogg1 DNA glycosylases. Cancer Res 2004 Jul 1 4
30 15293549 The defense mechanisms in mammalian cells against oxidative damage in nucleic acids and their involvement in the suppression of mutagenesis and cell death. Free Radic Res 2004 May 2
31 15298724 Detection of a mouse OGG1 fragment during caspase-dependent apoptosis: oxidative DNA damage and apoptosis. Cancer Sci 2004 Aug 8
32 15474421 Cell cycle regulation of the murine 8-oxoguanine DNA glycosylase (mOGG1): mOGG1 associates with microtubules during interphase and mitosis. DNA Repair (Amst) 2004 Dec 2 2
33 15677345 Potential role for 8-oxoguanine DNA glycosylase in regulating inflammation. FASEB J 2005 Feb 2
34 15721984 No evidence of mitochondrial respiratory dysfunction in OGG1-null mice deficient in removal of 8-oxodeoxyguanine from mitochondrial DNA. Free Radic Biol Med 2005 Mar 15 2
35 15778095 Substantial decrease of urinary 8-oxo-7,8-dihydroguanine, a product of the base excision repair pathway, in DNA glycosylase defective mice. Int J Biochem Cell Biol 2005 Jun 2
36 16024598 8-Oxoguanine formation induced by chronic UVB exposure makes Ogg1 knockout mice susceptible to skin carcinogenesis. Cancer Res 2005 Jul 15 2
37 16081118 Molecular and biochemical mechanisms in teratogenesis involving reactive oxygen species. Toxicol Appl Pharmacol 2005 Sep 1 1
38 16221681 Repair of formamidopyrimidines in DNA involves different glycosylases: role of the OGG1, NTH1, and NEIL1 enzymes. J Biol Chem 2005 Dec 9 1
39 16358418 Lack of the DNA repair enzyme OGG1 sensitizes dopamine neurons to manganese toxicity during development. Gene Expr 2005 5
40 16467516 MTH1, an oxidized purine nucleoside triphosphatase, suppresses the accumulation of oxidative damage of nucleic acids in the hippocampal microglia during kainate-induced excitotoxicity. J Neurosci 2006 Feb 8 1
41 16494984 The study using wild-type and Ogg1 knockout mice exposed to potassium bromate shows no tumor induction despite an extensive accumulation of 8-hydroxyguanine in kidney DNA. Toxicology 2006 Apr 17 2
42 16606334 Mutagenesis and carcinogenesis caused by the oxidation of nucleic acids. Biol Chem 2006 Apr 1
43 16698074 Oxidative damage produced by Cr(VI) and repair in mussel (Mytilus edulis L.) gill. Mar Environ Res 2006 Jul 2
44 16769088 Different DNA repair strategies to combat the threat from 8-oxoguanine. Mutat Res 2007 Jan 3 1
45 16831462 Neuroanatomical mapping of DNA repair and antioxidative responses in mouse brain: Effects of a single dose of MPTP. Neurotoxicology 2006 Dec 1
46 16961812 Deficiency in OGG1 protects against inflammation and mutagenic effects associated with H. pylori infection in mouse. Helicobacter 2006 Oct 1
47 17003489 Contrasting genome-wide distribution of 8-hydroxyguanine and acrolein-modified adenine during oxidative stress-induced renal carcinogenesis. Am J Pathol 2006 Oct 2
48 17251034 Site-directed photoproteolysis of 8-oxoguanine DNA glycosylase 1 (OGG1) by specific porphyrin-protein probe conjugates: a strategy to improve the effectiveness of photodynamic therapy for cancer. J Photochem Photobiol B 2007 Apr 2 13
49 17364943 Repeated inhalations of diesel exhaust particles and oxidatively damaged DNA in young oxoguanine DNA glycosylase (OGG1) deficient mice. Free Radic Res 2007 Feb 2
50 17441966 Carcinogenicity of dimethylarsinic acid in Ogg1-deficient mice. Cancer Sci 2007 Jun 14