Protein Name 8-oxoguanine DNA-glycosylase 1
Organism Mus musculus
Gene ID 18294
Gene Symbol

Ogg1

UniProt O08760 (OGG1_MOUSE), Q3UIL3 (Q3UIL3_MOUSE)
Relationships Total Number of functionally related compound(s) : 154
Total Number of Articles : 166
Description

8-oxoguanine DNA-glycosylase 1

Gene Summary

Enables 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity and microtubule binding activity. Acts upstream of or within base-excision repair. Located in mitochondrion and nucleus. Is expressed in junctional zone and labyrinthine zone. Human ortholog(s) of this gene implicated in several diseases, including Graves' disease; artery disease (multiple); carcinoma (multiple); eye disease (multiple); and reproductive organ cancer (multiple). Orthologous to human OGG1 (8-oxoguanine DNA glycosylase). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • N-glycosylase/DNA lyase
  • Mmh
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Properties