Title : MUTYH prevents OGG1 or APEX1 from inappropriately processing its substrate or reaction product with its C-terminal domain.

Pub. Date : 2004

PMID : 15199168






1 Functional Relationships(s)
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Protein Name
Organism
1 Wild-type mMUTYH bound duplex oligonucleotides containing A:8-oxoG pair with a lower apparent K(d) than that of the mutants, and prevented OGG1 from excising 8-oxoG opposite adenine or the generated AP site. Adenine 8-oxoguanine DNA-glycosylase 1 Mus musculus