Title : Substantial decrease of urinary 8-oxo-7,8-dihydroguanine, a product of the base excision repair pathway, in DNA glycosylase defective mice.

Pub. Date : 2005 Jun

PMID : 15778095






2 Functional Relationships(s)
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1 Our study revealed a 26% reduction in urinary level of 8-oxo-7,8-dihydroguanine in OGG1 deficient mice in comparison with the wild type strain. 8-hydroxyguanine 8-oxoguanine DNA-glycosylase 1 Mus musculus
2 This clearly indicates that the mouse OGG1 glycosylase contributes significantly to the generation of urinary 8-oxo-7,8-dihydroguanine. 8-hydroxyguanine 8-oxoguanine DNA-glycosylase 1 Mus musculus