Title : The defense mechanisms in mammalian cells against oxidative damage in nucleic acids and their involvement in the suppression of mutagenesis and cell death.

Pub. Date : 2004 May

PMID : 15293549






2 Functional Relationships(s)
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1 The increased occurrence of lung tumors in OGG1-null mice was abolished by the concomitant disruption of the Mth1 gene, indicating that an increased accumulation of 8-oxoG and/or 2-OH-A might cause cell death. 8-oxog 8-oxoguanine DNA-glycosylase 1 Mus musculus
2 The increased occurrence of lung tumors in OGG1-null mice was abolished by the concomitant disruption of the Mth1 gene, indicating that an increased accumulation of 8-oxoG and/or 2-OH-A might cause cell death. 2-oh-a 8-oxoguanine DNA-glycosylase 1 Mus musculus