Title : A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage.

Pub. Date : 2002 Nov 28

PMID : 12447686






1 Functional Relationships(s)
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1 Compared to ogg1(-/-) mice, csb(-/-)/ogg1(-/-) mice were found to accumulate with age severalfold higher levels of oxidited purine modifications in hepatocytes, splenocytes and kidney cells. purine 8-oxoguanine DNA-glycosylase 1 Mus musculus