| 1 | 10665479 | Antiandrogens in prostate cancer. | Invest New Drugs | 1999 |
1 |
| 2 | 17574413 | Synthesis and SAR of tetrahydropyrrolo[1,2-b][1,2,5]thiadiazol-2(3H)-one 1,1-dioxide analogues as highly potent selective androgen receptor modulators. | Bioorg Med Chem Lett | 2007 Aug 15 |
2 |
| 3 | 18086831 | Aryl-propionamide-derived selective androgen receptor modulators: liquid chromatography-tandem mass spectrometry characterization of the in vitro synthesized metabolites for doping control purposes. | Drug Metab Dispos | 2008 Mar |
2 |
| 4 | 18270691 | Determination of benzimidazole- and bicyclic hydantoin-derived selective androgen receptor antagonists and agonists in human urine using LC-MS/MS. | Anal Bioanal Chem | 2008 May |
1 |
| 5 | 18442912 | Discovery of a novel series of nonsteroidal androgen receptor modulators: 5- or 6-oxachrysen-2-ones. | Bioorg Med Chem Lett | 2008 Jun 1 |
2 |
| 6 | 19351168 | N-aryl-oxazolidin-2-imine muscle selective androgen receptor modulators enhance potency through pharmacophore reorientation. | J Med Chem | 2009 May 14 |
2 |
| 7 | 19837372 | Tissue-specific activities of an immune signaling module regulate physiological responses to pathogenic and nutritional bacteria in C. elegans. | Cell Host Microbe | 2009 Oct 22 |
1 |
| 8 | 19846549 | Identification of anabolic selective androgen receptor modulators with reduced activities in reproductive tissues and sebaceous glands. | J Biol Chem | 2009 Dec 25 |
1 |
| 9 | 20355219 | Detection of the arylpropionamide-derived selective androgen receptor modulator (SARM) S-4 (Andarine) in a black-market product. | Drug Test Anal | 2009 Aug |
2 |
| 10 | 20534726 | Effects of a novel selective androgen receptor modulator on dexamethasone-induced and hypogonadism-induced muscle atrophy. | Endocrinology | 2010 Aug |
2 |
| 11 | 20623476 | Mass spectrometric characterization of urinary metabolites of the selective androgen receptor modulator andarine (S-4) for routine doping control purposes. | Rapid Commun Mass Spectrom | 2010 Aug 15 |
1 |
| 12 | 21165606 | Validation of a GC/MS method for the detection of two quinolinone-derived selective androgen receptor modulators in doping control analysis. | Anal Bioanal Chem | 2011 Apr |
1 |
| 13 | 21538997 | Trafficking of drug candidates relevant for sports drug testing: detection of non-approved therapeutics categorized as anabolic and gene doping agents in products distributed via the Internet. | Drug Test Anal | 2011 May |
1 |
| 14 | 21867721 | Facile radiosynthesis of new carbon-11-labeled propanamide derivatives as selective androgen receptor modulator (SARM) radioligands for prostate cancer imaging. | Steroids | 2011 Dec 11 |
6 |
| 15 | 22031847 | The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial. | J Cachexia Sarcopenia Muscle | 2011 Sep |
1 |
| 16 | 22366489 | Molecular characterization of porcine SARM1 and its role in regulating TLRs signaling during highly pathogenic porcine reproductive and respiratory syndrome virus infection in vivo. | Dev Comp Immunol | 2013 Jan-Feb |
2 |
| 17 | 23175186 | T-cell death following immune activation is mediated by mitochondria-localized SARM. | Cell Death Differ | 2013 Mar |
1 |
| 18 | 23732550 | A phase IIA randomized, placebo-controlled clinical trial to study the efficacy and safety of the selective androgen receptor modulator (SARM), MK-0773 in female participants with sarcopenia. | J Nutr Health Aging | 2013 |
3 |
| 19 | 23885119 | SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria. | Mol Biol Cell | 2013 Sep |
2 |
| 20 | 24273094 | Lead evaluation of tetrahydroquinolines as nonsteroidal selective androgen receptor modulators for the treatment of osteoporosis. | ChemMedChem | 2014 Jan |
2 |
| 21 | 24478430 | Resveratrol inhibits the TRIF-dependent pathway by upregulating sterile alpha and armadillo motif protein, contributing to anti-inflammatory effects after respiratory syncytial virus infection. | J Virol | 2014 Apr |
5 |
| 22 | 24786833 | Ubiquitination by SAG regulates macrophage survival/death and immune response during infection. | Cell Death Differ | 2014 Sep |
1 |
| 23 | 25594179 | Pathological axonal death through a MAPK cascade that triggers a local energy deficit. | Cell | 2015 Jan 15 |
2 |
| 24 | 25816983 | Telmisartan attenuated LPS-induced neuroinflammation in human IMR-32 neuronal cell line via SARM in AT1R independent mechanism. | Life Sci | 2015 Jun 1 |
1 |
| 25 | 25906032 | In vitro metabolism studies on the selective androgen receptor modulator (SARM) LG121071 and its implementation into human doping controls using liquid chromatography-mass spectrometry. | Eur J Mass Spectrom (Chichester) | 2015 |
2 |
| 26 | 26268046 | Beyond TLR Signaling—The Role of SARM in Antiviral Immune Defense, Apoptosis & Development. | Int Rev Immunol | 2015 |
1 |
| 27 | 26592460 | SARM modulates MyD88-mediated TLR activation through BB-loop dependent TIR-TIR interactions. | Biochim Biophys Acta | 2016 Feb |
3 |
| 28 | 26683992 | 2-Chloro-4-[[(1R,2R)-2-hydroxy-2-methyl-cyclopentyl]amino]-3-methyl-benzonitrile: A Transdermal Selective Androgen Receptor Modulator (SARM) for Muscle Atrophy. | J Med Chem | 2016 Jan 28 |
2 |
| 29 | 27511110 | Risk of false positive results to SARM S-4 in case of therapeutic use of antineoplastic/antiandrogen drug containing flutamide: a case study. | Drug Test Anal | 2016 Nov |
1 |
| 30 | 27551463 | SAG-UPS attenuates proapoptotic SARM and Noxa to confer survival advantage to early hepatocellular carcinoma. | Cell Death Discov | 2015 |
5 |
| 31 | 27726308 | Selective androgen receptor modulators: comparative excretion study of bicalutamide in bovine urine and faeces. | Drug Test Anal | 2017 Jul |
1 |
| 32 | 28095293 | MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2. | Elife | 2017 Jan 17 |
2 |
| 33 | 28334607 | The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD<sup>+</sup> Cleavage Activity that Promotes Pathological Axonal Degeneration. | Neuron | 2017 Mar 22 |
10 |
| 34 | 28440570 | Mass spectrometric characterization of the selective androgen receptor modulator (SARM) YK-11 for doping control purposes. | Rapid Commun Mass Spectrom | 2017 Jul 30 |
3 |
| 35 | 28449232 | Safety, pharmacokinetics and pharmacological effects of the selective androgen receptor modulator, GSK2881078, in healthy men and postmenopausal women. | Br J Clin Pharmacol | 2017 Oct |
1 |
| 36 | 29232975 | Mass spectrometric studies on selective androgen receptor modulators (SARMs) using electron ionization and electrospray ionization/collision-induced dissociation. | Eur J Mass Spectrom (Chichester) | 2018 Feb |
1 |
| 37 | 29319101 | Structural elucidation of major selective androgen receptor modulator (SARM) metabolites for doping control. | Org Biomol Chem | 2018 Jan 31 |
2 |
| 38 | 29395922 | TIR Domain Proteins Are an Ancient Family of NAD<sup>+</sup>-Consuming Enzymes. | Curr Biol | 2018 Feb 5 |
2 |
| 39 | 29527831 | Development of a selective androgen receptor modulator for transdermal use in hypogonadal patients. | Andrology | 2018 May |
2 |
| 40 | 29982690 | GSK2881078, a SARM, Produces Dose-Dependent Increases in Lean Mass in Healthy Older Men and Women. | J Clin Endocrinol Metab | 2018 Sep 1 |
1 |
| 41 | 30257945 | Pharmacological bypass of NAD<sup>+</sup> salvage pathway protects neurons from chemotherapy-induced degeneration. | Proc Natl Acad Sci U S A | 2018 Oct 16 |
2 |
| 42 | 30333228 | c-Jun N-terminal kinase (JNK)-mediated phosphorylation of SARM1 regulates NAD<sup>+</sup> cleavage activity to inhibit mitochondrial respiration. | J Biol Chem | 2018 Dec 7 |
9 |
| 43 | 30633870 | SARM: From immune regulator to cell executioner. | Biochem Pharmacol | 2019 Mar |
3 |
| 44 | 31053351 | Development and validation of a semi-quantitative ultra-high performance liquid chromatography-tandem mass spectrometry method for screening of selective androgen receptor modulators in urine. | J Chromatogr A | 2019 Aug 30 |
2 |
| 45 | 31128467 | A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell Death. | iScience | 2019 May 31 |
10 |
| 46 | 31278906 | Structural Evidence for an Octameric Ring Arrangement of SARM1. | J Mol Biol | 2019 Sep 6 |
8 |
| 47 | 31439792 | NAD<sup>+</sup> cleavage activity by animal and plant TIR domains in cell death pathways. | Science | 2019 Aug 23 |
7 |
| 48 | 31439793 | TIR domains of plant immune receptors are NAD<sup>+</sup>-cleaving enzymes that promote cell death. | Science | 2019 Aug 23 |
3 |
| 49 | 31484833 | Vincristine and bortezomib use distinct upstream mechanisms to activate a common SARM1-dependent axon degeneration program. | JCI Insight | 2019 Sep 5 |
6 |
| 50 | 31672920 | Resolving the topological enigma in Ca<sup>2+</sup> signaling by cyclic ADP-ribose and NAADP. | J Biol Chem | 2019 Dec 27 |
6 |