Title : Pharmacological bypass of NAD+ salvage pathway protects neurons from chemotherapy-induced degeneration.

Pub. Date : 2018 Oct 16

PMID : 30257945






2 Functional Relationships(s)
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1 Axon degeneration, a hallmark of chemotherapy-induced peripheral neuropathy (CIPN), is thought to be caused by a loss of the essential metabolite nicotinamide adenine dinucleotide (NAD+) via the prodegenerative protein SARM1. NAD sterile alpha and TIR motif containing 1 Homo sapiens
2 Axon degeneration, a hallmark of chemotherapy-induced peripheral neuropathy (CIPN), is thought to be caused by a loss of the essential metabolite nicotinamide adenine dinucleotide (NAD+) via the prodegenerative protein SARM1. NAD sterile alpha and TIR motif containing 1 Homo sapiens