CPRiL

Protein Name	sterile alpha and TIR motif containing 1
Organism	Homo sapiens
Gene ID	23098
Gene Symbol	SARM1
UniProt	Q6SZW1 (SARM1_HUMAN), Q0D2N8 (Q0D2N8_HUMAN), Q05B42 (Q05B42_HUMAN)
Relationships	Total Number of functionally related compound(s) : 76 Total Number of Articles : 80
Description	sterile alpha and TIR motif containing 1
Gene Summary	Enables NAD+ nucleosidase activity; NAD+ nucleosidase activity, cyclic ADP-ribose generating; and identical protein binding activity. Involved in NAD+ catabolic process and response to axon injury. Is active in mitochondrion. [provided by Alliance of Genome Resources, Jun 2025]
synonyms	NAD(+) hydrolase SARM1 NADP(+) hydrolase SARM1 NADase SARM1 SAM domain-containing protein 2 sterile alpha and Armadillo repeat protein sterile alpha and HEAT/Armadillo motif protein, ortholog of Drosophila sterile alpha and TIR motif-containing protein 1 sterile alpha motif domain-containing protein 2 tir-1 homolog HsTIR MyD88-5 SAMD2 SARM hSARM1 Click to show/hide the synonyms
Properties