Pub. Date : 2016 Feb
PMID : 26592460
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A single glycine residue located in the BB-loop of the SARM TIR domain, G601, was identified as essential for interaction. | Glycine | sterile alpha and TIR motif containing 1 | Homo sapiens |
| 2 | The same result was observed with cytokine activation initiated by MyD88 expression and stimulation of TLR2 with lipoteichoic acid (LTA), suggesting that SARM is capable of suppressing both TRIF- and MyD88- dependent TLR signalling. | lipoteichoic acid | sterile alpha and TIR motif containing 1 | Homo sapiens |
| 3 | The same result was observed with cytokine activation initiated by MyD88 expression and stimulation of TLR2 with lipoteichoic acid (LTA), suggesting that SARM is capable of suppressing both TRIF- and MyD88- dependent TLR signalling. | lipoteichoic acid | sterile alpha and TIR motif containing 1 | Homo sapiens |