401 | 31814016 | Dienogest regulates apoptosis, proliferation, and invasiveness of endometriotic cyst stromal cells via endoplasmic reticulum stress induction. | Mol Hum Reprod | 2020 Jan 1 |
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402 | 31912702 | Long noncoding RNA-regulator of reprogramming alleviates hypoxia-induced cerebral injury in mice model and human via modulating apoptosis complexes. | J Integr Neurosci | 2019 Dec 30 |
4 |
403 | 31922706 | Moderate hyperoxia plays a protective role in lung bronchial epithelial cells. | Clin Invest Med | 2019 Dec 29 |
1 |
404 | 31926625 | Modification of Cys residues in human thioredoxin-1 by p-benzoquinone causes inhibition of its catalytic activity and activation of the ASK1/p38-MAPK signalling pathway. | Redox Biol | 2020 Jan |
5 |
405 | 31952288 | Endoplasmic Reticulum Stress Contributes to Indomethacin-Induced Glioma Apoptosis. | Int J Mol Sci | 2020 Jan 15 |
3 |
406 | 32006563 | H<sub>2</sub>S attenuates injury after ischemic stroke by diminishing the assembly of CaMKII with ASK1-MKK3-p38 signaling module. | Behav Brain Res | 2020 Apr 20 |
3 |
407 | 32124968 | Histone deacetylase inhibitor OBP‑801 and amrubicin synergistically inhibit the growth of squamous cell lung carcinoma by inducing mitochondrial ASK1‑dependent apoptosis. | Int J Oncol | 2020 Mar |
12 |
408 | 32147362 | Selonsertib for patients with bridging fibrosis or compensated cirrhosis due to NASH: Results from randomized phase III STELLAR trials. | J Hepatol | 2020 Jul |
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409 | 32289582 | Discovery of a 2-pyridinyl urea-containing compound YD57 as a potent inhibitor of apoptosis signal-regulating kinase 1 (ASK1). | Eur J Med Chem | 2020 Jun 1 |
5 |
410 | 32452100 | Tumour-associated macrophages as a novel target of VEGI-251 in cancer therapy. | J Cell Mol Med | 2020 Jul |
2 |
411 | 32544093 | Chronic-plus-binge alcohol intake induces production of proinflammatory mtDNA-enriched extracellular vesicles and steatohepatitis via ASK1/p38MAPKα-dependent mechanisms. | JCI Insight | 2020 Jul 23 |
8 |
412 | 32640963 | Periplogenin Activates ROS-ER Stress Pathway to Trigger Apoptosis via BIP-eIF2α- CHOP and IRE1α-ASK1-JNK Signaling Routes. | Anticancer Agents Med Chem | 2021 |
5 |
413 | 32717251 | Involvement of endoplasmic reticulum stress response and IRE1-mediated ASK1/JNK/Mcl-1 pathways in silver nanoparticle-induced apoptosis of human retinal pigment epithelial cells. | Toxicology | 2020 Sep |
2 |
414 | 32841541 | Phase II trial of sorafenib and doxorubicin in patients with advanced hepatocellular carcinoma after disease progression on sorafenib. | Cancer Med | 2020 Oct |
2 |
415 | 32876895 | MicroRNA-532-3p Regulates Pro-Inflammatory Human THP-1 Macrophages by Targeting ASK1/p38 MAPK Pathway. | Inflammation | 2021 Feb |
1 |
416 | 32982289 | Theabrownin Induces Apoptosis and Tumor Inhibition of Hepatocellular Carcinoma Huh7 Cells Through ASK1-JNK-c-Jun Pathway. | Onco Targets Ther | 2020 |
1 |
417 | 32984087 | Regulation of Cellular Stress Signaling in Bladder Ischemia. | Res Rep Urol | 2020 |
1 |
418 | 32996404 | <i>In silico</i> and <i>in vitro</i> investigations on the protein-protein interactions of glutathione S-transferases with mitogen-activated protein kinase 8 and apoptosis signal-regulating kinase 1. | J Biomol Struct Dyn | 2022 Feb |
1 |
419 | 33039870 | Bisphenol A induces apoptosis through GPER-dependent activation of the ROS/Ca<sup>2+</sup>-ASK1-JNK pathway in human granulosa cell line KGN. | Ecotoxicol Environ Saf | 2021 Jan 15 |
5 |
420 | 33108364 | β-adrenergic receptor signaling evokes the PKA-ASK axis in mature brown adipocytes. | PLoS One | 2020 |
2 |
421 | 33189448 | Bisphenol AF induces apoptosis via estrogen receptor beta (ERβ) and ROS-ASK1-JNK MAPK pathway in human granulosa cell line KGN. | Environ Pollut | 2021 Feb 1 |
3 |
422 | 33251987 | Role of cardiac drugs and flavonoids on the IRE1-JNK pathway as revealed by re-ranked molecular docking scores, MM/PBSA and umbrella sampling. | J Biomol Struct Dyn | 2022 May |
3 |
423 | 33348022 | Endoplasmic reticulum stress in doxorubicin-induced cardiotoxicity may be therapeutically targeted by natural and chemical compounds: A review. | Pharmacol Res | 2021 Feb |
1 |
424 | 33360793 | Structure-based discovery of 1H-indole-2-carboxamide derivatives as potent ASK1 inhibitors for potential treatment of ulcerative colitis. | Eur J Med Chem | 2021 Feb 5 |
1 |
425 | 33524379 | RIPK1 inhibitor ameliorates the MPP<sup>+</sup>/MPTP-induced Parkinson's disease through the ASK1/JNK signalling pathway. | Brain Res | 2021 Apr 15 |
1 |
426 | 33631173 | Apoptosis signal-regulating kinase 1 inhibition reverses deleterious indoxyl sulfate-mediated endothelial effects. | Life Sci | 2021 May 1 |
5 |
427 | 33667419 | Computational model of cardiomyocyte apoptosis identifies mechanisms of tyrosine kinase inhibitor-induced cardiotoxicity. | J Mol Cell Cardiol | 2021 Jun |
1 |
428 | 33692842 | Wogonoside promotes apoptosis and ER stress in human gastric cancer cells by regulating the IRE1α pathway. | Exp Ther Med | 2021 Apr |
2 |
429 | 33781891 | Epigenetic silencing of GCH1promotes hepatocellular carcinoma growth by activating superoxide anion-mediated ASK1/p38 signaling via inhibiting tetrahydrobiopterin de novo biosynthesis. | Free Radic Biol Med | 2021 May 20 |
6 |
430 | 33857660 | Apoptosis signal-regulating kinase 1 (ASK1) inhibition reduces endothelial cytokine production without improving permeability after toll-like receptor 4 (TLR4) challenge. | Transl Res | 2021 Sep |
1 |
431 | 33906048 | Design, synthesis and biological evaluation of 1H-indazole derivatives as novel ASK1 inhibitors. | Eur J Med Chem | 2021 Aug 5 |
2 |
432 | 33907844 | Vanillin downregulates NNMT and attenuates NNMT‑related resistance to 5‑fluorouracil via ROS‑induced cell apoptosis in colorectal cancer cells. | Oncol Rep | 2021 Jun |
2 |
433 | 33920356 | Endoplasmic Reticulum Stress Contributes to Gefitinib-Induced Apoptosis in Glioma. | Int J Mol Sci | 2021 Apr 11 |
1 |
434 | 33990641 | trans-Fatty acids promote p53-dependent apoptosis triggered by cisplatin-induced DNA interstrand crosslinks via the Nox-RIP1-ASK1-MAPK pathway. | Sci Rep | 2021 May 14 |
8 |
435 | 34020281 | Cadmium induces apoptosis of human granulosa cell line KGN via mitochondrial dysfunction-mediated pathways. | Ecotoxicol Environ Saf | 2021 Sep 1 |
1 |
436 | 34070036 | Epigenetic Insights and Potential Modifiers as Therapeutic Targets in <i>β</i>-Thalassemia. | Biomolecules | 2021 May 18 |
1 |
437 | 34133989 | Activation of type 4 metabotropic glutamate receptor attenuates oxygen and glucose deprivation-induced apoptosis in human neural stem cells via inhibition of ASK1-p38 signaling pathway. | Brain Res | 2021 Sep 15 |
1 |
438 | 34144391 | Proteasome dysfunction under compromised redox metabolism dictates liver injury in NASH through ASK1/PPARγ binodal complementary modules. | Redox Biol | 2021 Sep |
2 |
439 | 34158609 | Glutathione peroxidase-1 regulates ASK1-dependent apoptosis via interaction with TRAF2 in RIPK3-negative cancer cells. | Exp Mol Med | 2021 Jun |
2 |
440 | 34209102 | Prdx1 Interacts with ASK1 upon Exposure to H<sub>2</sub>O<sub>2</sub> and Independently of a Scaffolding Protein. | Antioxidants (Basel) | 2021 Jun 30 |
2 |
441 | 34348125 | Apocynin attenuates diabetic cardiomyopathy by suppressing ASK1-p38/JNK signaling. | Eur J Pharmacol | 2021 Oct 15 |
1 |
442 | 34389432 | A novel protein encoded by circASK1 ameliorates gefitinib resistance in lung adenocarcinoma by competitively activating ASK1-dependent apoptosis. | Cancer Lett | 2021 Nov 1 |
3 |
443 | 34427546 | Ketamine enhances autophagy and endoplasmic reticulum stress in rats and SV-HUC-1 cells via activating IRE1-TRAF2-ASK1-JNK pathway. | Cell Cycle | 2021 Sep |
1 |
444 | 34440075 | Au<sub>2</sub>phen and Auoxo6, Two Dinuclear Oxo-Bridged Gold(III) Compounds, Induce Apoptotic Signaling in Human Ovarian A2780 Cancer Cells. | Biomedicines | 2021 Jul 23 |
2 |
445 | 34498942 | PDK4 Decrease Neuronal Apoptosis <i>via</i> Inhibiting ROS-ASK1/P38 Pathway in Early Brain Injury After Subarachnoid Hemorrhage. | Antioxid Redox Signal | 2022 Mar |
2 |
446 | 34560123 | Enhanced GRP78 protein expression via the IRE1α/ASK1/p38 MAPK pathway during As<sub>2</sub>O<sub>3</sub>-induced endoplasmic reticulum stress in BEAS-2B cells. | Toxicology | 2021 Oct |
2 |
447 | 34732784 | Thioredoxin-1 mediates neuroprotection of Schisanhenol against MPP<sup>+</sup>-induced apoptosis via suppression of ASK1-P38-NF-κB pathway in SH-SY5Y cells. | Sci Rep | 2021 Nov 3 |
2 |
448 | 34850538 | Surfactin induces ER stress-mediated apoptosis via IRE1-ASK1-JNK signaling in human osteosarcoma. | Environ Toxicol | 2022 Mar |
3 |
449 | 34895315 | Trichomonas vaginalis induces apoptosis via ROS and ER stress response through ER-mitochondria crosstalk in SiHa cells. | Parasit Vectors | 2021 Dec 11 |
1 |
450 | 34948191 | Structural Insights Support Targeting ASK1 Kinase for Therapeutic Interventions. | Int J Mol Sci | 2021 Dec 13 |
2 |