Title : Apoptosis signal-regulating kinase 1 (ASK1) inhibition reduces endothelial cytokine production without improving permeability after toll-like receptor 4 (TLR4) challenge.

Pub. Date : 2021 Sep

PMID : 33857660






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Two ASK1 inhibitors, GS444217 and MSC2023964A, reduced cytokine production in HMVECs following LPS stimulation, but had no effect on permeability as measured by transendothelial electrical resistance (TEER) and intercellular space. ASK1-IN-1 mitogen-activated protein kinase kinase kinase 5 Homo sapiens