T-box 21 ; Mus musculus






138 Article(s)
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1 12296295 A role for the peroxisome proliferator-activated receptor alpha in T-cell physiology and ageing immunobiology. Proc Nutr Soc 2002 Aug 1
2 14741432 Chronic morphine treatment differentiates T helper cells to Th2 effector cells by modulating transcription factors GATA 3 and T-bet. J Neuroimmunol 2004 Feb 2
3 15007632 T cell directives for transcriptional regulation in asthma. Springer Semin Immunopathol 2004 Feb 1
4 15304658 Evolutionarily conserved sequence elements that positively regulate IFN-gamma expression in T cells. Proc Natl Acad Sci U S A 2004 Aug 24 1
5 15569414 Immunoenhancing activity of protopanaxatriol-type ginsenoside-F3 in murine spleen cells. Acta Pharmacol Sin 2004 Dec 2
6 15770538 Protopanaxatriol-type ginsenosides differentially modulate type 1 and type 2 cytokines production from murine splenocytes. Planta Med 2005 Mar 2
7 16115380 Effects of CpG oligodeoxynucleotide on transcription factors GATA-3 and T-bet mRNA expression in asthmatic mice. Acta Pharmacol Sin 2005 Sep 2
8 16143131 CpG motifs of bacterial DNA essentially contribute to the perpetuation of chronic intestinal inflammation. Gastroenterology 2005 Sep 1
9 16179640 T-bet polymorphisms are associated with asthma and airway hyperresponsiveness. Am J Respir Crit Care Med 2006 Jan 1 1
10 16393272 Oral administration of pulverized Konjac glucomannan prevents the increase of plasma immunoglobulin E and immunoglobulin G levels induced by the injection of syngeneic keratinocyte extracts in BALB/c mice. Clin Exp Allergy 2006 Jan 1
11 16648243 Increased bleomycin-induced lung injury in mice deficient in the transcription factor T-bet. Am J Physiol Lung Cell Mol Physiol 2006 Oct 1
12 16880257 T-bet negatively regulates autoimmune myocarditis by suppressing local production of interleukin 17. J Exp Med 2006 Aug 7 1
13 17174308 D-pinitol regulates Th1/Th2 balance via suppressing Th2 immune response in ovalbumin-induced asthma. FEBS Lett 2007 Jan 9 1
14 17307869 Transcription factor T-bet regulates skin sclerosis through its function in innate immunity and via IL-13. Proc Natl Acad Sci U S A 2007 Feb 20 3
15 17314493 Increased bleomycin-induced skin fibrosis in mice lacking the Th1-specific transcription factor T-bet. Pathobiology 2006 4
16 17566144 Diosgenin, a steroidal sapogenin, enhances antigen-specific IgG2a and interferon-gamma expression in ovalbumin-sensitized BALB/c mice. Planta Med 2007 May 1
17 17625103 Gemfibrozil ameliorates relapsing-remitting experimental autoimmune encephalomyelitis independent of peroxisome proliferator-activated receptor-alpha. Mol Pharmacol 2007 Oct 3
18 18096152 Suppression of allergen-induced airway inflammation and immune response by the peroxisome proliferator-activated receptor-alpha agonist fenofibrate. Eur J Pharmacol 2008 Feb 26 1
19 18638450 Lycopene suppresses ovalbumin-induced airway inflammation in a murine model of asthma. Biochem Biophys Res Commun 2008 Sep 19 1
20 18664394 The therapeutic effect of TV-5010 in a murine model of inflammatory bowel disease -- Dextran induced colitis. Int Immunopharmacol 2008 Nov 1
21 19061976 Quercetin regulates Th1/Th2 balance in a murine model of asthma. Int Immunopharmacol 2009 Mar 1
22 19645570 Suppression of Th1- and Th2-type immune responses in infant mouse spleen after prenatal and postnatal exposure to low-level toluene and peptidoglycan. Inhal Toxicol 2009 Aug 1
23 19698701 Novel immunomodulatory properties of cirsilineol through selective inhibition of IFN-gamma signaling in a murine model of inflammatory bowel disease. Biochem Pharmacol 2010 Jan 15 2
24 19698774 Immunosuppressive effects of an ethyl acetate extract from Urtica dentata Hand on skin allograft rejection. J Ethnopharmacol 2009 Oct 29 1
25 19799960 Docosahexaenoic acid modulates the expression of T-bet and GATA-3 transcription factors, independently of PPARalpha, through suppression of MAP kinase activation. Biochimie 2009 Nov-Dec 2
26 20361943 Obaculactone suppresses Th1 effector cell function through down-regulation of T-bet and prolongs skin graft survival in mice. Biochem Pharmacol 2010 Jul 15 2
27 20434553 Paclitaxel acts as an adjuvant to promote both Th1 and Th2 immune responses induced by ovalbumin in mice. Vaccine 2010 Jun 17 1
28 20505765 Immunological basis for the gender differences in murine Paracoccidioides brasiliensis infection. PLoS One 2010 May 21 1
29 20580249 The modulative effect of Cyperi Rhizoma on Th1/Th2 lineage development. Cytokine 2010 Sep 1
30 21093428 Jaceosidin inhibits contact hypersensitivity in mice via down-regulating IFN-γ/STAT1/T-bet signaling in T cells. Eur J Pharmacol 2011 Jan 25 5
31 21135031 Induction of tolerogenic lung CD4+ T cells by local treatment with a pSTAT-3 and pSTAT-5 inhibitor ameliorated experimental allergic asthma. Int Immunol 2011 Jan 2
32 21383241 Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550). J Immunol 2011 Apr 1 1
33 21601613 Dysregulation of immune responses in an allergic mouse model following low-level toluene exposure. Toxicology 2011 Aug 15 1
34 21690296 c-Abl-mediated tyrosine phosphorylation of the T-bet DNA-binding domain regulates CD4+ T-cell differentiation and allergic lung inflammation. Mol Cell Biol 2011 Aug 4
35 21813204 Serine protease inhibitor, 4-(2-aminoethyl)-benzene sulfonyl fluoride, impairs IL-12-induced activation of pSTAT4β, NFκB, and select pro-inflammatory mediators from estrogen-treated mice. Immunobiology 2011 Dec 1
36 21905017 Overexpression of T-bet gene regulates murine autoimmune arthritis. Arthritis Rheum 2012 Jan 2
37 22082615 The ΔfbpA attenuated candidate vaccine from Mycobacterium tuberculosis, H37Rv primes for a stronger T-bet dependent Th1 immunity in mice. Tuberculosis (Edinb) 2011 Dec 3
38 22318143 The histone deacetylase inhibitor valproic acid lessens NK cell action against oncolytic virus-infected glioblastoma cells by inhibition of STAT5/T-BET signaling and generation of gamma interferon. J Virol 2012 Apr 1
39 22496903 Compound A, a dissociated glucocorticoid receptor modulator, inhibits T-bet (Th1) and induces GATA-3 (Th2) activity in immune cells. PLoS One 2012 1
40 22508471 Genistein attenuated allergic airway inflammation by modulating the transcription factors T-bet, GATA-3 and STAT-6 in a murine model of asthma. Pharmacology 2012 1
41 22697007 Cellulose sulfate suppresses immunoglobulin E production by murine B lymphocytes in vitro. J Investig Allergol Clin Immunol 2012 1
42 22890814 Nitric oxide inhibits the accumulation of CD4+CD44hiTbet+CD69lo T cells in mycobacterial infection. Eur J Immunol 2012 Dec 2
43 22901686 The role of T-bet in obesity: lack of T-bet causes obesity in male mice. J Nutr Biochem 2013 Jan 1
44 22958289 Modulation of FLT3 signaling targets conventional dendritic cells to attenuate acute lung injury. APMIS 2012 Oct 1
45 22962611 Dietary resveratrol prevents the development of food allergy in mice. PLoS One 2012 1
46 23095308 Lymphocyte-derived catecholamines induce a shift of Th1/Th2 balance toward Th2 polarization. Neuroimmunomodulation 2013 1
47 23178269 The Th1/Th2/Th17/Treg paradigm induced by stachydrine hydrochloride reduces uterine bleeding in RU486-induced abortion mice. J Ethnopharmacol 2013 Jan 9 1
48 23222894 A color-coded reporter model to study the effect of immunosuppressants on CD8+ T-cell memory in antitumor and alloimmune responses. Transplantation 2013 Jan 15 1
49 23328383 [FLT3 signaling manipulates conventional dendritic cells to regulate acute lung injury]. Zhonghua Yi Xue Za Zhi 2012 Nov 20 1
50 23520167 Angiotensin II-induced vascular dysfunction depends on interferon-γ-driven immune cell recruitment and mutual activation of monocytes and NK-cells. Arterioscler Thromb Vasc Biol 2013 Jun 2