Title : A color-coded reporter model to study the effect of immunosuppressants on CD8+ T-cell memory in antitumor and alloimmune responses.

Pub. Date : 2013 Jan 15

PMID : 23222894






1 Functional Relationships(s)
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1 Rapamycin, but not tacrolimus, induced a pro-antitumor phenotypic shift from CD62LCD44 effector memory Tc cells to CD62LCD44 central memory Tc cells, which featured up-regulated levels of T-bet and Eomes and preserved levels of interferon-gamma and perforin. Sirolimus T-box 21 Mus musculus