2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid






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51 24648336 miR-335 correlates with senescence/aging in human mesenchymal stem cells and inhibits their therapeutic actions through inhibition of AP-1 activity. Stem Cells 2014 Aug 1
52 24832598 Senescence induced by RECQL4 dysfunction contributes to Rothmund-Thomson syndrome features in mice. Cell Death Dis 2014 May 15 1
53 24966955 Initiation of premature senescence by Bcl-2 in hypoxic condition. Int J Clin Exp Pathol 2014 3
54 25118260 TAK1 inhibition accelerates cellular senescence of retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 2014 Aug 12 1
55 25345622 Cellular senescence occurred widespread to multiple selective sites in the fetal tissues and organs of mice. Clin Exp Pharmacol Physiol 2014 Dec 1
56 25486783 [Differences in defense mechanisms against oxidative stress in both human embryonic and endometrium-derived mesenchymal stem cells]. Tsitologiia 2013 2
57 25652587 The histone demethylase jumonji coordinates cellular senescence including secretion of neural stem cell-attracting cytokines. Mol Cancer Res 2015 Apr 2
58 25664004 SIRT1 counteracted the activation of STAT3 and NF-κB to repress the gastric cancer growth. Int J Clin Exp Med 2014 1
59 25676326 Chemical constituents of Hericium erinaceum associated with the inhibitory activity against cellular senescence in human umbilical vascular endothelial cells. J Enzyme Inhib Med Chem 2015 Dec 1
60 25736378 Shp2 signaling suppresses senescence in PyMT-induced mammary gland cancer in mice. EMBO J 2015 Jun 3 1
61 25765721 Restoring SIRT6 Expression in Hutchinson-Gilford Progeria Syndrome Cells Impedes Premature Senescence and Formation of Dysmorphic Nuclei. Pathobiology 2015 1
62 25766527 Gas6 delays senescence in vascular smooth muscle cells through the PI3K/ Akt/FoxO signaling pathway. Cell Physiol Biochem 2015 1
63 25876105 Overexpression of the novel senescence marker β-galactosidase (GLB1) in prostate cancer predicts reduced PSA recurrence. PLoS One 2015 1
64 25924011 Resveratrol Induced Premature Senescence Is Associated with DNA Damage Mediated SIRT1 and SIRT2 Down-Regulation. PLoS One 2015 2
65 26058854 The retinoic acid-metabolizing enzyme CYP26A1 upregulates fascin and promotes the malignant behavior of breast carcinoma cells. Oncol Rep 2015 Aug 1
66 26230157 Serum- and Glucocorticoid-Inducible Kinase 1 Delay the Onset of Endothelial Senescence by Directly Interacting with Human Telomerase Reverse Transcriptase. Rejuvenation Res 2016 Feb 3
67 26289253 Endothelial autophagy and Endothelial-to-Mesenchymal Transition (EndoMT) in eEPC treatment of ischemic AKI. J Nephrol 2016 Oct 1
68 26397719 Telomere Fragment Induced Amnion Cell Senescence: A Contributor to Parturition? PLoS One 2015 2
69 26639398 Overexpression of Sirtuin 6 suppresses cellular senescence and NF-κB mediated inflammatory responses in osteoarthritis development. Sci Rep 2015 Dec 7 1
70 26654351 Knockdown of SIRT6 Enables Human Bone Marrow Mesenchymal Stem Cell Senescence. Rejuvenation Res 2016 Oct 1
71 27259243 Estrogen receptor alpha inhibits senescence-like phenotype and facilitates transformation induced by oncogenic ras in human mammary epithelial cells. Oncotarget 2016 Jun 28 2
72 27294914 Protective Effect of Ginsenoside Rg1 on Hematopoietic Stem/Progenitor Cells through Attenuating Oxidative Stress and the Wnt/β-Catenin Signaling Pathway in a Mouse Model of d-Galactose-induced Aging. Int J Mol Sci 2016 Jun 9 1
73 27498005 Cartilage oligomeric matrix protein prevents vascular aging and vascular smooth muscle cells senescence. Biochem Biophys Res Commun 2016 Sep 16 2
74 27617860 Interruption of progerin-lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotype. J Clin Invest 2016 Oct 3 1
75 27713146 TGF-β and NF-κB signaling pathway crosstalk potentiates corneal epithelial senescence through an RNA stress response. Aging (Albany NY) 2016 Oct 6 1
76 27888541 TWEAK increases SIRT1 expression and promotes p53 deacetylation affecting human hepatic stellate cell senescence. Cell Biol Int 2017 Feb 1
77 27902467 Autocrine IL-6 mediates pituitary tumor senescence. Oncotarget 2017 Jan 17 1
78 27956701 The Chromatin-Associated Phf12 Protein Maintains Nucleolar Integrity and Prevents Premature Cellular Senescence. Mol Cell Biol 2017 Mar 1 1
79 28197300 Long-Term Treatment of Native LDL Induces Senescence of Cultured Human Endothelial Cells. Oxid Med Cell Longev 2017 2
80 28211497 The inflammatory cytokine TNF-α promotes the premature senescence of rat nucleus pulposus cells via the PI3K/Akt signaling pathway. Sci Rep 2017 Feb 17 1
81 28234906 Persistence of senescent prostate cancer cells following prolonged neoadjuvant androgen deprivation therapy. PLoS One 2017 1
82 28356293 Urinary DcR2 is a novel biomarker for tubulointerstitial injury in patients with diabetic nephropathy. Am J Physiol Renal Physiol 2017 Aug 1 1
83 28461078 Isolation and identification of senescent renal tubular epithelial cells using immunomagnetic beads based on DcR2. Exp Gerontol 2017 Sep 1
84 28536075 Increased chemo-sensitivity by knockdown coilin expression involved acceleration of premature cellular senescence in HeLa cells. Biochem Biophys Res Commun 2017 Jul 22 1
85 28591988 [Correlation between Mic60 haploid insufficiency and cardiac aging in mouse]. Zhonghua Bing Li Xue Za Zhi 2017 Jun 8 1
86 28894133 5-methoxytryptophan protects MSCs from stress induced premature senescence by upregulating FoxO3a and mTOR. Sci Rep 2017 Sep 11 3
87 28894504 An Extract from the Plant <i>Deschampsia antarctica</i> Protects Fibroblasts from Senescence Induced by Hydrogen Peroxide. Oxid Med Cell Longev 2017 1
88 28992616 NS1 of H7N9 Influenza A Virus Induces NO-Mediated Cellular Senescence in Neuro2a Cells. Cell Physiol Biochem 2017 1
89 29176033 TNFα-senescence initiates a STAT-dependent positive feedback loop, leading to a sustained interferon signature, DNA damage, and cytokine secretion. Aging (Albany NY) 2017 Nov 22 1
90 29352261 Insight into the role of PIKK family members and NF-кB in DNAdamage-induced senescence and senescence-associated secretory phenotype of colon cancer cells. Cell Death Dis 2018 Jan 19 1
91 29367112 Osteogenic protein-1 attenuates the inflammatory cytokine-induced NP cell senescence through regulating the ROS/NF-κB pathway. Biomed Pharmacother 2018 Mar 1
92 29436649 Interleukin‑10 promotes primary rat hepatic stellate cell senescence by upregulating the expression levels of p53 and p21. Mol Med Rep 2018 Apr 1
93 29440765 Baicalin induces cellular senescence in human colon cancer cells via upregulation of DEPP and the activation of Ras/Raf/MEK/ERK signaling. Cell Death Dis 2018 Feb 13 4
94 29565449 DNA damage induced by human CD40 ligand mutant promotes senescence and induces demethylation of GATA4 in lung cancer. Oncol Rep 2018 May 1
95 29587204 Leukotriene D4 induces cellular senescence in osteoblasts. Int Immunopharmacol 2018 May 1
96 29804242 Elevated levels of the small GTPase Cdc42 induces senescence in male rat mesenchymal stem cells. Biogerontology 2018 Jul 1
97 30003648 Monoamine oxidase-A is a novel driver of stress-induced premature senescence through inhibition of parkin-mediated mitophagy. Aging Cell 2018 Oct 1
98 30079478 Matrine induces senescence of human glioblastoma cells through suppression of the IGF1/PI3K/AKT/p27 signaling pathway. Cancer Med 2018 Sep 2
99 30265659 Accelerated Glomerular Cell Senescence in Experimental Lupus Nephritis. Med Sci Monit 2018 Sep 28 1
100 30270410 Self-assembled protein-enzyme nanoflower-based fluorescent sensing for protein biomarker. Anal Bioanal Chem 2018 Nov 2