Title : Long-Term Treatment of Native LDL Induces Senescence of Cultured Human Endothelial Cells.

Pub. Date : 2017

PMID : 28197300






2 Functional Relationships(s)
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1 The causative factor of the cellular senescence was nLDL itself and not oxidized LDL (oxLDL), since blocking LDL receptor (LDLR) with the anti-LDLR antibody opposed the nLDL-induced increase of SA-beta-Gal activity and decrease of cellular proliferation. 2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid low density lipoprotein receptor Homo sapiens
2 The causative factor of the cellular senescence was nLDL itself and not oxidized LDL (oxLDL), since blocking LDL receptor (LDLR) with the anti-LDLR antibody opposed the nLDL-induced increase of SA-beta-Gal activity and decrease of cellular proliferation. 2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid low density lipoprotein receptor Homo sapiens