Memantine






481 Article(s)
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51 15099690 The presence of the APP(swe) mutation in mice does not increase the vulnerability of cholinergic basal forebrain neurons to neuroinflammation. Neuroscience 2004 1
52 15192085 Memantine improves spatial learning in a transgenic mouse model of Alzheimer's disease. J Pharmacol Exp Ther 2004 Nov 1
53 15222774 What are the treatment options for patients with severe Alzheimer's disease? CNS Drugs 2004 1
54 15228642 Evidence-based pharmacotherapy of Alzheimer's disease. Int J Neuropsychopharmacol 2004 Sep 1
55 15266045 Lack of pharmacokinetic or pharmacodynamic interaction between memantine and donepezil. Ann Pharmacother 2004 Sep 3
56 15275830 Co-administration of memantine has no effect on the in vitro or ex vivo determined acetylcholinesterase inhibition of rivastigmine in the rat brain. Neuropharmacology 2004 Sep 1
57 15281522 Intraarticular pretreatment with ketamine and memantine could prevent arthritic pain: relevance to the decrease of spinal c-fos expression in rats. Anesth Analg 2004 Jul 2
58 15307296 [The clinical relevance of memantine use]. Psychiatr Pol 2004 Mar-Apr 1
59 15372325 Effect of memantine on the alpha 7 neuronal nicotinic receptors, synaptophysin- and low molecular weight MAP-2 levels in the brain of transgenic mice over-expressing human acetylcholinesterase. J Neural Transm (Vienna) 2005 Feb 5
60 15378224 Inhibitory effects of memantine on human cytochrome P450 activities: prediction of in vivo drug interactions. Eur J Clin Pharmacol 2004 Oct 11
61 15452358 Brain but not spinal NR2B receptor is responsible for the anti-allodynic effect of an NR2B subunit-selective antagonist CP-101,606 in a rat chronic constriction injury model. Pharmacology 2005 Jan 1
62 15522999 Memantine blocks alpha7* nicotinic acetylcholine receptors more potently than n-methyl-D-aspartate receptors in rat hippocampal neurons. J Pharmacol Exp Ther 2005 Mar 3
63 15901795 Pharmacological implications of two distinct mechanisms of interaction of memantine with N-methyl-D-aspartate-gated channels. J Pharmacol Exp Ther 2005 Sep 7
64 16009352 Memantine inhibits ethanol-induced NMDA receptor up-regulation in rat hippocampal neurons. Brain Res 2005 Aug 9 3
65 16107786 Memantine reduces hematoma expansion in experimental intracerebral hemorrhage, resulting in functional improvement. J Cereb Blood Flow Metab 2006 Apr 12
66 16262676 Memantine prolongs survival in an amyotrophic lateral sclerosis mouse model. Eur J Neurosci 2005 Nov 3
67 16289784 Involvement of PKA, MAPK/ERK and CaMKII, but not PKC in the acute antidepressant-like effect of memantine in mice. Neurosci Lett 2006 Mar 6 3
68 16298481 Amantadine and memantine induce the expression of the glial cell line-derived neurotrophic factor in C6 glioma cells. Neurosci Lett 2006 Feb 20 3
69 16354790 Effect of subchronic treatment of memantine, galantamine, and nicotine in the brain of Tg2576 (APPswe) transgenic mice. J Pharmacol Exp Ther 2006 Apr 2
70 16386235 Memantine attenuates staurosporine-induced activation of caspase-3 and LDH release in mouse primary neuronal cultures. Brain Res 2006 Jan 19 2
71 16464655 In vivo regulation of GSK3 phosphorylation by cholinergic and NMDA receptors. Neurobiol Aging 2006 Mar 3
72 16518518 Anticholinesterase toxicity and oxidative stress. ScientificWorldJournal 2006 Feb 28 1
73 16625572 Memantine for dementia. Cochrane Database Syst Rev 2006 Apr 19 1
74 16670247 A responder analysis of memantine treatment in patients with Alzheimer disease maintained on donepezil. Am J Geriatr Psychiatry 2006 May 1
75 16806196 Involvement of I2PP2A in the abnormal hyperphosphorylation of tau and its reversal by Memantine. FEBS Lett 2006 Jul 10 2
76 16859831 Conantokins and variants derived from cone snail venom inhibit naloxone-induced withdrawal jumping in morphine-dependent mice. Neurosci Lett 2006 Sep 11 1
77 16959224 Memantine reduces striatal cell death with decreasing calpain level in 3-nitropropionic model of Huntington's disease. Brain Res 2006 Nov 6 3
78 16989956 Memantine protects against LPS-induced neuroinflammation, restores behaviorally-induced gene expression and spatial learning in the rat. Neuroscience 2006 Nov 3 3
79 17033976 [Retrospective comparative analysis of antidementia medication persistence patterns in Spanish Alzheimer's disease patients treated with donepezil, rivastigmine, galantamine and memantine]. Rev Neurol 2006 Oct 16-31 1
80 17188316 Neuronal oxidative injury and dendritic damage induced by carbofuran: protection by memantine. Toxicol Appl Pharmacol 2007 Mar 1
81 17196560 NMDA receptor-mediated excitotoxicity contributes to the cerebral hypoxic injury of a rat model of posthypoxic myoclonus. Brain Res 2007 Feb 16 1
82 17251419 Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease. J Neurosci 2007 Jan 24 1
83 17267580 Effects of pan- and subtype-selective N-methyl-D-aspartate receptor antagonists on cortical spreading depression in the rat: therapeutic potential for migraine. J Pharmacol Exp Ther 2007 May 1
84 17308309 Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine. J Biol Chem 2007 Apr 13 1
85 17334274 Memantine treatment of cognitive symptoms in mild to moderate Alzheimer disease: secondary analyses from a placebo-controlled randomized trial. Alzheimer Dis Assoc Disord 2007 Jan-Mar 2
86 17466645 Effective pharmacologic management of Alzheimer's disease. Am J Med 2007 May 1
87 17469692 Treatment of moderate to severe Alzheimer's disease: rationale and trial design. Can J Neurol Sci 2007 Mar 1
88 17700020 Reduction of phosphorylated tau during memantine treatment of Alzheimer's disease. Dement Geriatr Cogn Disord 2007 2
89 17700645 Acute injections of the NMDA receptor antagonist memantine rescue performance deficits of the Ts65Dn mouse model of Down syndrome on a fear conditioning test. Neuropsychopharmacology 2008 Jun 5
90 17942238 Expression of N-methyl-d-aspartate receptor 1 in rats with chronic ocular hypertension. Neuroscience 2007 Nov 23 1
91 17962329 Mg2+ and memantine block of rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes. J Physiol 2008 Jan 1 4
92 17980434 Memantine prevents MDMA-induced neurotoxicity. Neurotoxicology 2008 Jan 1
93 17996985 The attenuating effect of memantine on staurosporine-, salsolinol- and doxorubicin-induced apoptosis in human neuroblastoma SH-SY5Y cells. Neurochem Int 2008 Mar-Apr 3
94 18000814 Memantine agonist action at dopamine D2High receptors. Synapse 2008 Feb 1
95 18288936 Memantine treatment in patients with mild to moderate Alzheimer's disease already receiving a cholinesterase inhibitor: a randomized, double-blind, placebo-controlled trial. Curr Alzheimer Res 2008 Feb 2
96 18346200 Amyloid beta peptide and NMDA induce ROS from NADPH oxidase and AA release from cytosolic phospholipase A2 in cortical neurons. J Neurochem 2008 Jul 2
97 18418360 Effects of memantine on neuronal structure and conditioned fear in the Tg2576 mouse model of Alzheimer's disease. Neuropsychopharmacology 2008 Dec 2
98 18434534 Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine. J Neurosci 2008 Apr 23 3
99 18456253 Memantine does not show intracellular block of the NMDA receptor channel. Eur J Pharmacol 2008 Jun 10 1
100 18486118 Neuroprotective effects of memantine in a mouse model of retinal degeneration induced by rotenone. Brain Res 2008 Jun 18 2