Title : Effects of pan- and subtype-selective N-methyl-D-aspartate receptor antagonists on cortical spreading depression in the rat: therapeutic potential for migraine.

Pub. Date : 2007 May

PMID : 17267580






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 These results indicate that NR2B-containing NMDA receptors are key mediators of SD, and as such, memantine- and NR2B-selective antagonists may be useful new therapeutic agents for the treatment of migraine and other SD-related disorders (e.g., stroke and brain injury). Memantine glutamate ionotropic receptor NMDA type subunit 2B Rattus norvegicus